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MPP7 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3211216

This is a rabbit polyclonal antibody against MPP7. It was validated on Western Blot using a cell lysate as a positive control.Target Description: MPP7 acts as an important adapter that promotes epithelial cell polarity and tight junction formation via its… More details

$490 / 0.1 mL +1 FREE 8GB USB
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Product Overview

Online Datasheet in PDF
Product Name
MPP7, Polyclonal Antibody
Full Product Name
MPP7 antibody - N-terminal region
Product Gene Name
Product Synonym Gene Name
FLJ32798; RP11-218D6.5
Immunogen Sequence
Synthetic peptide located within the following region: MPALSTGSGS DTGLYELLAA LPAQLQPHVD SQEDLTFLWD MFGEKSLHSL
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Tested: Human; Predicted: Cow, Dog, Horse, Human, Mouse, Rabbit, Rat
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Purity/Purification
Affinity Purified
Concentration
Batch dependent within range: 100 ul at 0.5 - 1 mg/ml (lot specific)
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Antibody/Peptide Pairs
MPP7 peptide (MBS3236168) is used for blocking the activity of MPP7 antibody (MBS3211216)
Molecular Weight
65kDa
OMIM
610973
3D Structure
ModBase 3D Structure for Q5T2T1
Protein Size (#AA)
576 amino acids
Protein Interactions
AMOT; Wwtr1; Yap1; UBC
Blocking Peptide
For anti-MPP7 (MBS3211216) antibody is MBS3236168
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human MPP7
Predicted Homology Based on Immunogen Sequence
Cow: 100%; Dog: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%
Replacement Item
This antibody may replace item sc-163089 from Santa Cruz Biotechnology.
Applications Tested/Suitable for anti-MPP7 antibody
Western Blot (WB)

Western Blot (WB) of anti-MPP7 antibody

WB Suggested Anti-MPP7 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: HT1080 cell lysate
Rabbit Anti-MPP7 Polyclonal Antibody – Cat# MBS3211216

Other Notes

Small volumes of anti-MPP7 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MPP7 purchase

MBS3211216 is an antibody targeting MPP7. Also known as MPP7 antibody - N-terminal region. Reactive in Tested: Human; Predicted: Cow, Dog, Horse, Human, Mouse, Rabbit, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for MPP7. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
MAGUK p55 subfamily member 7
NCBI Official Synonym Full Names
membrane palmitoylated protein 7
NCBI Official Symbol
MPP7
UniProt Protein Name
MAGUK p55 subfamily member 7
Protein Family
UniProt Gene Name
MPP7
UniProt Entry Name
MPP7_HUMAN
NCBI Protein Information
MAGUK p55 subfamily member 7

NCBI Summary for MPP7

The protein encoded by this gene is a member of the p55 Stardust family of membrane-associated guanylate kinase (MAGUK) proteins, which function in the establishment of epithelial cell polarity. This family member forms a complex with the polarity protein DLG1 (discs, large homolog 1) and facilitates epithelial cell polarity and tight junction formation. Polymorphisms in this gene are associated with variations in site-specific bone mineral density (BMD). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
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UniProt Comments for MPP7

MPP7: Acts as an important adapter that promotes epithelial cell polarity and tight junction formation via its interaction with DLG1. Involved in the assembly of protein complexes at sites of cell-cell contact. Belongs to the MAGUK family.

Protein type: Adaptor/scaffold

Chromosomal Location of Human Ortholog: 10p12.1

Cellular Component: adherens junction; tight junction; mitochondrion; cell junction

Molecular Function: protein domain specific binding; protein binding; protein heterodimerization activity; protein complex scaffold

Biological Process: positive regulation of protein complex assembly; positive regulation of signal transduction; establishment of cell polarity
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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