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ZCCHC12 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3211233

This is a rabbit polyclonal antibody against ZCCHC12. It was validated on Western Blot using a cell lysate as a positive control.Target Description: ZCCHC12 contains 1 CCHC-type zinc finger. ZCCHC12 is the transcriptional coactivator in the bone morphogenetic… More details

$490 / 0.1 mL +1 FREE 8GB USB
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Product Overview

Online Datasheet in PDF
Product Name
ZCCHC12, Polyclonal Antibody
Full Product Name
ZCCHC12 antibody - middle region
Product Gene Name
Product Synonym Gene Name
FLJ16123; SIZN; SIZN1; PNMA7A
Immunogen Sequence
Synthetic peptide located within the following region: EKASLYVIRL EVQLQNAIQA GIIAEKDANR TRLQQLLLGG ELSRDLRLRL
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Purity/Purification
Affinity Purified
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Antibody/Peptide Pairs
ZCCHC12 peptide (MBS3236185) is used for blocking the activity of ZCCHC12 antibody (MBS3211233)
Molecular Weight
45kDa
OMIM
AK122676 mRNA
3D Structure
ModBase 3D Structure for Q6PEW1
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human ZCCHC12
Applications Tested/Suitable for anti-ZCCHC12 antibody
Western Blot (WB)

Western Blot (WB) of anti-ZCCHC12 antibody

WB Suggested Anti-ZCCHC12 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: Human Stomach
Rabbit Anti-ZCCHC12 Polyclonal Antibody – Cat# MBS3211233

Other Notes

Small volumes of anti-ZCCHC12 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ZCCHC12 purchase

MBS3211233 is an antibody targeting ZCCHC12. Also known as ZCCHC12 antibody - middle region. Reactive in Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for ZCCHC12. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
zinc finger CCHC domain-containing protein 12
NCBI Official Synonym Full Names
zinc finger CCHC-type containing 12
NCBI Official Symbol
ZCCHC12
NCBI Official Synonym Symbols
SIZN; SIZN1; PNMA7A
UniProt Protein Name
Zinc finger CCHC domain-containing protein 12
UniProt Synonym Protein Names
Smad-interacting zinc finger protein 1
UniProt Gene Name
ZCCHC12
UniProt Synonym Gene Names
SIZN1
NCBI Protein Information
zinc finger CCHC domain-containing protein 12

NCBI Summary for ZCCHC12

This gene encodes a downstream effector of bone morphogenetic protein (BMP) signalling. This protein contains a zinc finger domain and functions as a transcriptional coactivator. Variation in this gene may be associated with X-linked cognitive disability. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015]
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UniProt Comments for ZCCHC12

Transcriptional coactivator in the bone morphogenetic protein (BMP)-signaling pathway. It positively modulates BMP signaling by interacting with SMAD1 and associating with CBP in the transcription complex. It contributes to the BMP-induced enhancement of cholinergic-neuron-specific gene expression ().
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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