• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

COX18 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3212360

This is a rabbit polyclonal antibody against COX18. It was validated on Western BlotTarget Description: COX18 is required for the insertion of integral membrane proteins into the mitochondrial inner membrane. COX18 is essential for the activity and assembly… More details

$490 / 0.1 mL +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
COX18, Polyclonal Antibody
Full Product Name
COX18 antibody - middle region
Product Gene Name
Product Synonym Gene Name
COX18HS; FLJ38991; MGC126733
Immunogen Sequence
Synthetic peptide located within the following region: LVWIQLPMWI FMSFALRNLS TGAAHSEGFS VQEQLATGGI LWFPDLTAPD
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Purity/Purification
Affinity Purified
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Antibody/Peptide Pairs
COX18 peptide (MBS3237307) is used for blocking the activity of COX18 antibody (MBS3212360)
Molecular Weight
37kDa
OMIM
610428
3D Structure
ModBase 3D Structure for Q8N8Q8
Homology
Cow: 93%; Dog: 100%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 79%; Rabbit: 86%; Rat: 93%
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human COX18
Applications Tested/Suitable for anti-COX18 antibody
Western Blot (WB)

Western Blot (WB) of anti-COX18 antibody

WB Suggested Anti-COX18 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: ACHN cell lysate
Rabbit Anti-COX18 Polyclonal Antibody – Cat# MBS3212360

Other Notes

Small volumes of anti-COX18 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for COX18 purchase

MBS3212360 is an antibody targeting COX18. Also known as COX18 antibody - middle region. Reactive in Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for COX18. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
cytochrome c oxidase assembly protein COX18, mitochondrial isoform 2
NCBI Official Synonym Full Names
cytochrome c oxidase assembly factor COX18
NCBI Official Symbol
COX18
NCBI Official Synonym Symbols
COX18HS
UniProt Protein Name
Mitochondrial inner membrane protein COX18
UniProt Synonym Protein Names
Cytochrome c oxidase assembly protein 18
UniProt Gene Name
COX18
UniProt Synonym Gene Names
OXA1L2; COX18Hs
UniProt Entry Name
COX18_HUMAN
NCBI Protein Information
cytochrome c oxidase assembly protein COX18, mitochondrial

NCBI Summary for COX18

This gene encodes a cytochrome c oxidase assembly protein. The encoded protein is essential for integral membrane protein insertion into the mitochondrial inner membrane. It is also required for cytochrome c oxidase assembly and activity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
Show more

UniProt Comments for COX18

COX18: Required for the insertion of integral membrane proteins into the mitochondrial inner membrane. Essential for the activity and assembly of cytochrome c oxidase. Plays a central role in the translocation and export of the C-terminal part of the COX2 protein into the mitochondrial intermembrane space. Belongs to the OXA1/ALB3/YidC family. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Mitochondrial; Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 4q13.3

Cellular Component: integral to mitochondrial inner membrane

Molecular Function: protein transporter activity

Biological Process: protein transport; protein insertion into mitochondrial membrane; respiratory chain complex IV assembly
Show more

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with anti-COX18 antibody

 Organ/Tissue Name  Pubmed Publications
 Kidney Antibodies  >1 publications with COX18 and Kidney
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000