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RAGE (MOK) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3212970

This is a rabbit polyclonal antibody against RAGE. It was validated on Western BlotTarget Description: RAGE is able to phosphorylate several exogenous substrates and to undergo autophosphorylation. More details

$490 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
RAGE (MOK), Polyclonal Antibody
Full Product Name
RAGE antibody - middle region
Product Gene Name
Product Synonym Gene Name
MOK; RAGE1; RAGE; RAGE-1
Immunogen Sequence
Synthetic peptide located within the following region: TTNLSPQCLS LLHAMVAYDP DERIAAHQAL QHPYFQEQRK TEKRALGSHR
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Cow, Dog, Goat, Guinea Pig, Horse, Human, Mouse, Rabbit
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Purity/Purification
Affinity Purified
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Antibody/Peptide Pairs
RAGE peptide (MBS3237915) is used for blocking the activity of RAGE antibody (MBS3212970)
Molecular Weight
48kDa
OMIM
605762
3D Structure
ModBase 3D Structure for Q9UQ07
Homology
Cow: 93%; Dog: 93%; Goat: 79%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 93%
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human RAGE

Product Categories/Family for anti-MOK antibody

Applications Tested/Suitable for anti-MOK antibody
Western Blot (WB), Immunohistochemistry (IHC)

Immunohistochemistry (IHC) of anti-MOK antibody

Rabbit Anti-MOK Antibody
Formalin Fixed Paraffin Embedded Tissue: Human Testis Tissue
Observed Staining: Cytoplasm in spermatogonia and spermatocytes
Primary Antibody Concentration: 1:100
Other Working Concentrations: 1:600
Secondary Antibody: Donkey anti-Rabbit-Cy3
Secondary Antibody Concentration: 1:200
Magnification: 20X
Exposure Time: 0.5 - 2.0 sec
Rabbit Anti-MOK Polyclonal Antibody – Cat# MBS3212970

Western Blot (WB) of anti-MOK antibody

WB Suggested Anti-RAGE Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: OVCAR-3 cell lysate
Rabbit Anti-MOK Polyclonal Antibody, Western Blot (WB) – Cat# MBS3212970

Other Notes

Small volumes of anti-MOK antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MOK purchase

MBS3212970 is an antibody targeting MOK. Also known as RAGE antibody - middle region. Reactive in Cow, Dog, Goat, Guinea Pig, Horse, Human, Mouse, Rabbit. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for MOK. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
MAPK/MAK/MRK overlapping kinase isoform 1
NCBI Official Synonym Full Names
MOK protein kinase
NCBI Official Symbol
MOK
NCBI Official Synonym Symbols
RAGE; RAGE1; STK30; RAGE-1
UniProt Protein Name
MAPK/MAK/MRK overlapping kinase
UniProt Synonym Protein Names
MOK protein kinase; Renal tumor antigen 1
UniProt Gene Name
MOK
UniProt Synonym Gene Names
RAGE; RAGE1; RAGE-1
UniProt Entry Name
MOK_HUMAN
NCBI Protein Information
MAPK/MAK/MRK overlapping kinase

NCBI Summary for MOK

This gene belongs to the MAP kinase superfamily. The gene was found to be regulated by caudal type transcription factor 2 (Cdx2) protein. The encoded protein, which is localized to epithelial cells in the intestinal crypt, may play a role in growth arrest and differentiation of cells of upper crypt and lower villus regions. Multiple alternatively spliced transcript variants encoding different isoforms have been observed for this gene. [provided by RefSeq, Dec 2012]
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UniProt Comments for MOK

MOK: a CMGC protein kinase of the RCK family. Possesses a Thr-Glu-Tyr motif in the activation loop domain, as do classical MAP kinases. Associates with and is apparently stabilized by HSP90.

Protein type: EC 2.7.11.22; Protein kinase, CMGC; Protein kinase, Ser/Thr (non-receptor); Kinase, protein; CMGC group; RCK family

Chromosomal Location of Human Ortholog: 14q32

Cellular Component: cytoplasm

Molecular Function: protein serine/threonine kinase activity; cyclin-dependent protein kinase activity; ATP binding; protein kinase activity

Biological Process: regulation of cell cycle; signal transduction; protein amino acid phosphorylation
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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