Rabbit Anti-RRAGD Polyclonal Antibody – Cat# MBS3213415

Host: Rabbit
Target Name: RRAGD
Sample Tissue: Human OVCAR-3 Whole Cell lysates
Antibody Dilution: 1ug/ml

RRAGD Antibody – Rabbit Polyclonal

Name: RRAGD Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS3213415
Price: 490 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3213415

RRAGD is a monomeric guanine nucleotide-binding protein, or G protein. By binding GTP or GDP, small G proteins act as molecular switches in numerous cell processes and signaling pathways.[supplied by OMIM, Apr 2004] More details

$490 / 0.1 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

RRAGD, Polyclonal Antibody

Full Product Name

RRAGD Antibody - N-terminal region

Product Gene Name

anti-RRAGD antibody

Product Synonym Gene Name

RAGD; bA11D8.2.1

Immunogen Sequence

Synthetic peptide located within the following region: PQPQDEDDAE EEEEEDELVG LADYGDGPDS SDADPDSGTE EGVLDFSDPF

Clonality

Polyclonal

Host

Rabbit

Species Reactivity

Human

Form/Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 29% sucrose.

Purity/Purification

Affinity purified

Preparation and Storage

For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Antibody/Peptide Pairs

RRAGD peptide (MBS3238360) is used for blocking the activity of RRAGD antibody (MBS3213415)

Molecular Weight

45 kDa

OMIM

608268

3D Structure

ModBase 3D Structure for Q9NQL2

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human RRAGD

Product Categories/Family for anti-RRAGD antibody

Polyclonal; Signal Transduction; DNA/RNA/Protein Interactions

Applications Tested/Suitable for anti-RRAGD antibody

Western Blot (WB)

Other Notes

Small volumes of anti-RRAGD antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for RRAGD purchase

MBS3213415 is an antibody targeting RRAGD. Also known as RRAGD Antibody - N-terminal region. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for RRAGD. It may not necessarily be applicable to this product.

NCBI GI #

11034847

NCBI GeneID

58528

NCBI Accession #

NP_067067.1

UniProt Primary Accession #

Q9NQL2

UniProt Related Accession #

Q9NQL2

GenBank Nucleotide #

NM_021244.4

NCBI Official Full Name

ras-related GTP-binding protein D

NCBI Official Synonym Full Names

Ras related GTP binding D

NCBI Official Symbol

RRAGD

NCBI Official Synonym Symbols

RAGD; bA11D8.2.1

UniProt Protein Name

Ras-related GTP-binding protein D

Protein Family

Ras-related GTP-binding protein

UniProt Gene Name

RRAGD

UniProt Synonym Gene Names

Rag D; RagD

UniProt Entry Name

RRAGD_HUMAN

NCBI Protein Information

ras-related GTP-binding protein D

UniProt Comments for RRAGD

RRAGD: Has guanine nucleotide-binding activity but lacks intrinsic GTPase activity. Probably required for the amino acid- induced relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB. This is a crucial step in the activation of the TOR signaling cascade by amino acids. Forms a heterodimer with RRAGA in a sequence-independent manner. Binds GTP. Interacts with NOL8 and RRAGB. Belongs to the GTR/RAG GTP-binding protein family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: G protein regulator, misc.

Chromosomal Location of Human Ortholog: 6q15

Cellular Component: lysosome; cytoplasm; nucleus

Molecular Function: GTPase activity; protein binding; GDP binding; GTP binding; protein heterodimerization activity

Biological Process: metabolic process; regulation of autophagy; cellular response to starvation; positive regulation of TOR signaling pathway

Research Articles on RRAGD

1. BC-LI-0186 binds to the RagD interacting site of LRS, thereby inhibiting lysosomal localization of LRS and mTORC1 activity.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-RRAGD antibody

Reference Product	PubMed Publications
RRAGC antibody	>3 publications with RRAGD and RRAGC
RRAGA antibody	>2 publications with RRAGD and RRAGA
NOL8 antibody	>1 publications with RRAGD and NOL8
RRAGB antibody	>1 publications with RRAGD and RRAGB
RPTOR antibody	>1 publications with RRAGD and RPTOR
MTOR antibody	>1 publications with RRAGD and MTOR

Pathways associated with anti-RRAGD antibody

Products by Pathway	Pathway Diagram
TOR Signaling Pathway antibodies	TOR Signaling Pathway Diagram
MTOR Signaling Pathway antibodies	MTOR Signaling Pathway Diagram
MTOR Signaling Pathway antibodies	MTOR Signaling Pathway Diagram

Diseases associated with anti-RRAGD antibody

Disease Name	Pubmed Publications
Neoplasms Antibodies	>1 publications with RRAGD and Neoplasms
Heart Diseases Antibodies	>1 publications with RRAGD and Heart Diseases
Disease Models, Animal Antibodies	>1 publications with RRAGD and Disease Models, Animal
Cardiovascular Diseases Antibodies	>1 publications with RRAGD and Cardiovascular Diseases

Organs/Tissues associated with anti-RRAGD antibody

Organ/Tissue Name	Pubmed Publications
Connective Tissue Antibodies	>1 publications with RRAGD and Connective Tissue
Blood Antibodies	>1 publications with RRAGD and Blood
Intestine Antibodies	>1 publications with RRAGD and Intestine
Skin Antibodies	>1 publications with RRAGD and Skin
Heart Antibodies	>1 publications with RRAGD and Heart