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SLIT3 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3214044

This is a rabbit polyclonal antibody against SLIT3. It was validated on Western Blot using a cell lysate as a positive control.Target Description: SLIT3 may act as molecular guidance cue in cellular migration, and function may be mediated by interaction with… More details

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Product Overview

Online Datasheet in PDF
Product Name
SLIT3, Polyclonal Antibody
Full Product Name
SLIT3 antibody - N-terminal region
Product Gene Name
Product Synonym Gene Name
FLJ10764; MEGF5; SLIL2; SLIT1; Slit-3; slit2
Immunogen Sequence
Synthetic peptide located within the following region: PRRLANKRIS QIKSKKFRCS GSEDYRSRFS SECFMDLVCP EKCRCEGTIV
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Purity/Purification
Affinity Purified
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Antibody/Peptide Pairs
SLIT3 peptide (MBS3238982) is used for blocking the activity of SLIT3 antibody (MBS3214044)
Molecular Weight
168kDa
OMIM
603745
3D Structure
ModBase 3D Structure for O75094
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 93%; Rabbit: 93%; Rat: 93%
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human SLIT3
Applications Tested/Suitable for anti-SLIT3 antibody
Western Blot (WB)

Western Blot (WB) of anti-SLIT3 antibody

Host: Rabbit
Target Name: SLIT3
Sample Tissue: Human HT1080 Whole Cell
Antibody Dilution: 1ug/ml
Rabbit Anti-SLIT3 Polyclonal Antibody – Cat# MBS3214044

Western Blot (WB) of anti-SLIT3 antibody

WB Suggested Anti-SLIT3 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: Human Muscle
Rabbit Anti-SLIT3 Polyclonal Antibody, Western Blot (WB) – Cat# MBS3214044

Other Notes

Small volumes of anti-SLIT3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SLIT3 purchase

MBS3214044 is an antibody targeting SLIT3. Also known as SLIT3 antibody - N-terminal region. Reactive in Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for SLIT3. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
slit homolog 3 protein isoform 2
NCBI Official Synonym Full Names
slit guidance ligand 3
NCBI Official Symbol
SLIT3
NCBI Official Synonym Symbols
MEGF5; SLIL2; SLIT1; slit2; Slit-3
UniProt Protein Name
Slit homolog 3 protein
UniProt Synonym Protein Names
Multiple epidermal growth factor-like domains protein 5
UniProt Gene Name
SLIT3
UniProt Synonym Gene Names
KIAA0814; MEGF5; SLIL2; Slit-3
UniProt Entry Name
SLIT3_HUMAN
NCBI Protein Information
slit homolog 3 protein

NCBI Summary for SLIT3

The protein encoded by this gene is secreted, likely interacting with roundabout homolog receptors to effect cell migration. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2012]

UniProt Comments for SLIT3

SLIT3: May act as molecular guidance cue in cellular migration, and function may be mediated by interaction with roundabout homolog receptors. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 5q35

Cellular Component: extracellular space; mitochondrion

Molecular Function: Roundabout binding; calcium ion binding

Biological Process: axon extension involved in axon guidance; chemorepulsion involved in embryonic olfactory bulb interneuron migration; axon guidance; negative regulation of cell proliferation; organ morphogenesis; response to cortisol stimulus; negative chemotaxis; negative regulation of cell growth; cellular response to hormone stimulus
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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