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ADCYAP1R1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3214581

This is a rabbit polyclonal antibody against Adcyap1r1. It was validated on Western BlotTarget Description: Adcyap1r1 regulates neural precursor proliferation; mediates inhibitory signaling for Shh-induced cerebellar granule precursor cell proliferation. More details

$490 / 0.1 mL +1 FREE 8GB USB
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Product Overview

Online Datasheet in PDF
Product Name
Adcyap1r1, Polyclonal Antibody
Full Product Name
Adcyap1r1 antibody - C-terminal region
Product Gene Name
anti-ADCYAP1R1 antibody
Product Synonym Gene Name
PACAP-R1A; PACAPR1|PACAPR1A; PAC1-R; PACAPR1; PACAPR1A
Immunogen Sequence
Synthetic peptide located within the following region: GIIIILVQKL QSPDMGGNES SIYFSCVQKC YCKPQRAQQH SCKMSELSTI
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Sheep, Zebrafish
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Purity/Purification
Affinity Purified
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Antibody/Peptide Pairs
Adcyap1r1 peptide (MBS3239518) is used for blocking the activity of Adcyap1r1 antibody (MBS3214581)
Molecular Weight
54kDa
3D Structure
ModBase 3D Structure for P32215
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%; Sheep: 100%; Zebrafish: 93%

Product Categories/Family for anti-ADCYAP1R1 antibody

Polyclonal; Cell Adhesion; Stem Cells; Cell Differentiation
Applications Tested/Suitable for anti-ADCYAP1R1 antibody
Western Blot (WB), Immunohistochemistry (IHC)-F

Western Blot (WB) of anti-ADCYAP1R1 antibody

WB Suggested Anti-Adcyap1r1 Antibody
Titration: 1.0 ug/ml
Positive Control: Rat Brain
Rabbit Anti-ADCYAP1R1 Polyclonal Antibody – Cat# MBS3214581

Other Notes

Small volumes of anti-ADCYAP1R1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ADCYAP1R1 purchase

MBS3214581 is an antibody targeting ADCYAP1R1. Also known as Adcyap1r1 antibody - C-terminal region. Reactive in Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Sheep, Zebrafish. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for ADCYAP1R1. It may not necessarily be applicable to this product.

NCBI GI #
19424148
NCBI GeneID
24167
NCBI Accession #
NP_598195
UniProt Primary Accession #
P32215
UniProt Related Accession #
P32215
GenBank Nucleotide #
NM_133511
NCBI Official Full Name
pituitary adenylate cyclase-activating polypeptide type I receptor isoform b
NCBI Official Synonym Full Names
ADCYAP receptor type 1
NCBI Official Symbol
Adcyap1r1
NCBI Official Synonym Symbols
PAC1-R; PACAPR1; PACAP-R1; PACAPR1A; PACAP-R1A
UniProt Protein Name
Pituitary adenylate cyclase-activating polypeptide type I receptor
Protein Family
Pituitary adenylate cyclase-activating polypeptide type I receptor
UniProt Gene Name
Adcyap1r1
UniProt Synonym Gene Names
PACAP type I receptor; PACAP-R-1; PACAP-R1
UniProt Entry Name
PACR_RAT
NCBI Protein Information
pituitary adenylate cyclase-activating polypeptide type I receptor

NCBI Summary for ADCYAP1R1

regulates neural precursor proliferation; mediates inhibitory signaling for Shh-induced cerebellar granule precursor cell proliferation [RGD, Feb 2006]

UniProt Comments for ADCYAP1R1

ADCYAP1R1: This is a receptor for PACAP-27 and PACAP-38. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. May regulate the release of adrenocorticotropin, luteinizing hormone, growth hormone, prolactin, epinephrine, and catecholamine. May play a role in spermatogenesis and sperm motility. Causes smooth muscle relaxation and secretion in the gastrointestinal tract. Belongs to the G-protein coupled receptor 2 family. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Receptor, GPCR; Membrane protein, multi-pass; GPCR, family 2

Cellular Component: Golgi membrane; neuron projection; tight junction; cell surface; rough endoplasmic reticulum; cytoplasm; integral to membrane; caveola; receptor complex; endosome

Molecular Function: neuropeptide binding; ADP-ribosylation factor binding; vasoactive intestinal polypeptide receptor activity; adenylate cyclase binding

Biological Process: response to drug; development of primary female sexual characteristics; G-protein coupled receptor protein signaling pathway; cAMP-mediated signaling; response to ethanol; phospholipase C activation; positive regulation of cAMP biosynthetic process; spermatogenesis; cell differentiation; multicellular organismal response to stress; response to estradiol stimulus
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Research Articles on ADCYAP1R1

1. This study demonstrated that the hypothalamic PAC1 mRNA expression level fell after 24 h fasting in male rats, but no such changes were observed in the females.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-ADCYAP1R1 antibody

 Products by Pathway  Pathway Diagram
 Activation Of TRKA Receptors Pathway antibodies  Activation Of TRKA Receptors Pathway Diagram
 GPCRs, Class B Secretin-like Pathway antibodies  GPCRs, Class B Secretin-like Pathway Diagram
 NGF Signalling Via TRKA From The Plasma Membrane Pathway antibodies  NGF Signalling Via TRKA From The Plasma Membrane Pathway Diagram
 NGF-independant TRKA Activation Pathway antibodies  NGF-independant TRKA Activation Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
 SIDS Susceptibility Pathways antibodies  SIDS Susceptibility Pathways Diagram
 Signal Transduction Pathway antibodies  Signal Transduction Pathway Diagram
 Signalling By NGF Pathway antibodies  Signalling By NGF Pathway Diagram

Diseases associated with anti-ADCYAP1R1 antibody

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >20 publications with ADCYAP1R1 and Neoplasms
 Lung Neoplasms Antibodies  >6 publications with ADCYAP1R1 and Lung Neoplasms
 Gastrointestinal Diseases Antibodies  >6 publications with ADCYAP1R1 and Gastrointestinal Diseases
 Inflammation Antibodies  >5 publications with ADCYAP1R1 and Inflammation
 Drug Toxicity Antibodies  >3 publications with ADCYAP1R1 and Drug Toxicity
 Hypertrophy Antibodies  >2 publications with ADCYAP1R1 and Hypertrophy
 Necrosis Antibodies  >2 publications with ADCYAP1R1 and Necrosis
 Liver Diseases Antibodies  >2 publications with ADCYAP1R1 and Liver Diseases
 Liver Neoplasms, Experimental Antibodies  >2 publications with ADCYAP1R1 and Liver Neoplasms, Experimental
 Ischemia Antibodies  >2 publications with ADCYAP1R1 and Ischemia

Organs/Tissues associated with anti-ADCYAP1R1 antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >68 publications with ADCYAP1R1 and Brain
 Pituitary Gland Antibodies  >24 publications with ADCYAP1R1 and Pituitary Gland
 Uncharacterized Tissue Antibodies  >1 publications with ADCYAP1R1 and Uncharacterized Tissue
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