Rabbit Anti-H3F3A Polyclonal Antibody – Cat# MBS3215040

WB Suggested Anti-H3f3a Antibody
Titration: 1.0 ug/ml
Positive Control: Mouse Spleen

H3F3A Antibody – Rabbit Polyclonal

Name: H3F3A Antibody; Polyclonal; Rabbit; Pig/Rat-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS3215040
Price: 490 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3215040

This is a rabbit polyclonal antibody against H3f3a. It was validated on Western BlotTarget Description: H3f3a is a variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes. H3f3a constitutes the predominant form of… More details

$490 / 0.1 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

H3f3a, Polyclonal Antibody

Full Product Name

H3f3a antibody - N-terminal region

Product Gene Name

anti-H3F3A antibody

Product Synonym Gene Name

H3.3A; H3f3b; MGC102150

Immunogen Sequence

Synthetic peptide located within the following region: KSAPSTGGVK KPHRYRPGTV ALREIRRYQK STELLIRKLP FQRLVREIAQ

Clonality

Polyclonal

Host

Rabbit

Species Reactivity

Dog, Pig, Rat, Zebrafish

Form/Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Purity/Purification

Affinity Purified

Preparation and Storage

For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Antibody/Peptide Pairs

H3f3a peptide (MBS3239957) is used for blocking the activity of H3f3a antibody (MBS3215040)

Molecular Weight

15kDa

3D Structure

ModBase 3D Structure for P84244

Homology

Dog: 100%; Pig: 100%; Rat: 100%; Zebrafish: 100%

Product Categories/Family for anti-H3F3A antibody

Polyclonal; Cell Cycle Proteins; DNA/RNA/Protein Interactions

Applications Tested/Suitable for anti-H3F3A antibody

Western Blot (WB)

Other Notes

Small volumes of anti-H3F3A antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for H3F3A purchase

MBS3215040 is an antibody targeting H3F3A. Also known as H3f3a antibody - N-terminal region. Reactive in Dog, Pig, Rat, Zebrafish. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for H3F3A. It may not necessarily be applicable to this product.

NCBI GI #

6680159

NCBI GeneID

15078

NCBI Accession #

NP_032236

UniProt Primary Accession #

P84244

UniProt Related Accession #

P84244

GenBank Nucleotide #

NM_008210

NCBI Official Full Name

histone H3.3

NCBI Official Synonym Full Names

H3 histone, family 3A

NCBI Official Symbol

H3f3a

NCBI Official Synonym Symbols

H3.3A; EyeLinc14

UniProt Protein Name

Histone H3.3

UniProt Gene Name

H3f3a

UniProt Synonym Gene Names

H3.3a
H3f3b; H3.3b

UniProt Entry Name

H33_MOUSE

NCBI Protein Information

histone H3.3

NCBI Summary for H3F3A

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene contains introns and its mRNA is polyadenylated, unlike most histone genes. The protein encoded is a replication-independent member of the histone H3 family. [provided by RefSeq, Nov 2015]

Research Articles on H3F3A

1. Data (including data from studies using transgenic mice) suggest that H3f3a and H3f3b are required for (1) paternal chromatin remodeling, (2) development of preimplantation embryos, and (3) activation of paternal genome during embryogenesis.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-H3F3A antibody

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Diseases associated with anti-H3F3A antibody

Disease Name	Pubmed Publications
Neoplasms Antibodies	>4 publications with H3F3A and Neoplasms
Glioblastoma Antibodies	>2 publications with H3F3A and Glioblastoma
Kidney Neoplasms Antibodies	>1 publications with H3F3A and Kidney Neoplasms
Brain Diseases Antibodies	>1 publications with H3F3A and Brain Diseases
Nervous System Diseases Antibodies	>1 publications with H3F3A and Nervous System Diseases
Kidney Diseases Antibodies	>1 publications with H3F3A and Kidney Diseases
Pontine Glioma Antibodies	>1 publications with H3F3A and Pontine Glioma

Organs/Tissues associated with anti-H3F3A antibody

Organ/Tissue Name	Pubmed Publications
Kidney Antibodies	>1 publications with H3F3A and Kidney