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CCS Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3215048

This is a rabbit polyclonal antibody against CCS. It was validated on Western BlotTarget Description: Copper chaperone for superoxide dismutase specifically delivers Cu to copper/zinc superoxide dismutase and may activate copper/zinc superoxide dismutase… More details

$490 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CCS, Polyclonal Antibody
Full Product Name
CCS antibody - C-terminal region
Product Gene Name
anti-CCS antibody
Product Synonym Gene Name
MGC138260
Immunogen Sequence
Synthetic peptide located within the following region: LACGIIARSA GLFQNPKQIC SCDGLTIWEE RGRPIAGKGR KESAQPPAHL
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Cow, Dog, Horse, Human, Mouse, Pig, Rabbit, Rat
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Purity/Purification
Affinity Purified
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Antibody/Peptide Pairs
CCS peptide (MBS3239965) is used for blocking the activity of CCS antibody (MBS3215048)
Molecular Weight
29kDa
OMIM
603864
3D Structure
ModBase 3D Structure for O14618
Homology
Cow: 86%; Dog: 79%; Horse: 86%; Human: 100%; Mouse: 86%; Pig: 86%; Rabbit: 93%; Rat: 86%

Product Categories/Family for anti-CCS antibody

Polyclonal; Drugs and Drug Metabolism; Various; DNA/RNA/Protein Interactions
Applications Tested/Suitable for anti-CCS antibody
Western Blot (WB)

Western Blot (WB) of anti-CCS antibody

WB Suggested Anti-CCS Antibody
Titration: 1.0 ug/ml
Positive Control: MDA-MB-435S Whole CellCCS is supported by BioGPS gene expression data to be expressed in MDA-MB435
Rabbit Anti-CCS Polyclonal Antibody – Cat# MBS3215048

Other Notes

Small volumes of anti-CCS antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CCS purchase

MBS3215048 is an antibody targeting CCS. Also known as CCS antibody - C-terminal region. Reactive in Cow, Dog, Horse, Human, Mouse, Pig, Rabbit, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for CCS. It may not necessarily be applicable to this product.

NCBI GI #
4826665
NCBI GeneID
9973
NCBI Accession #
NP_005116
UniProt Primary Accession #
O14618
UniProt Related Accession #
O14618
GenBank Nucleotide #
NM_005125
NCBI Official Full Name
copper chaperone for superoxide dismutase
NCBI Official Synonym Full Names
copper chaperone for superoxide dismutase
NCBI Official Symbol
CCS
UniProt Protein Name
Copper chaperone for superoxide dismutase
UniProt Synonym Protein Names
Superoxide dismutase copper chaperone
Protein Family
Capsanthin/capsorubin synthase
UniProt Gene Name
CCS
UniProt Entry Name
CCS_HUMAN
NCBI Protein Information
copper chaperone for superoxide dismutase

NCBI Summary for CCS

Copper chaperone for superoxide dismutase specifically delivers Cu to copper/zinc superoxide dismutase and may activate copper/zinc superoxide dismutase through direct insertion of the Cu cofactor. [provided by RefSeq, Jul 2008]

UniProt Comments for CCS

CCS: Delivers copper to copper zinc superoxide dismutase (SOD1).

Chromosomal Location of Human Ortholog: 11q13

Cellular Component: cytoplasm; nucleus; cytosol

Molecular Function: copper ion transmembrane transporter activity; protein binding; copper ion binding; zinc ion binding; superoxide dismutase activity; protein disulfide oxidoreductase activity

Biological Process: response to reactive oxygen species; removal of superoxide radicals; superoxide metabolic process; intracellular copper ion transport; positive regulation of oxidoreductase activity
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Research Articles on CCS

1. In addition to Atox1, the human cytoplasm also contains Cu chaperones for loading of superoxide dismutase 1 (i.e. CCS) and cytochrome c oxidase in mitochondria (i.e. Cox17). [review]

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-CCS antibody

 Reference Product  PubMed Publications
 SOD1 antibody  >86 publications with CCS and SOD1
 APBA1 antibody  >3 publications with CCS and APBA1

Pathways associated with anti-CCS antibody

 Products by Pathway  Pathway Diagram
 Amyotrophic Lateral Sclerosis (ALS) Pathway antibodies  Amyotrophic Lateral Sclerosis (ALS) Pathway Diagram
 Amyotrophic Lateral Sclerosis (ALS) Pathway antibodies  Amyotrophic Lateral Sclerosis (ALS) Pathway Diagram

Diseases associated with anti-CCS antibody

 Disease Name  Pubmed Publications
 Heart Diseases Antibodies  >557 publications with CCS and Heart Diseases
 Neoplasms Antibodies  >449 publications with CCS and Neoplasms
 Nervous System Diseases Antibodies  >343 publications with CCS and Nervous System Diseases
 Neurologic Manifestations Antibodies  >151 publications with CCS and Neurologic Manifestations
 Inflammation Antibodies  >103 publications with CCS and Inflammation
 Disease Models, Animal Antibodies  >91 publications with CCS and Disease Models, Animal
 Hypertension Antibodies  >86 publications with CCS and Hypertension
 Liver Diseases Antibodies  >77 publications with CCS and Liver Diseases
 Necrosis Antibodies  >73 publications with CCS and Necrosis
 Neurodegenerative Diseases Antibodies  >71 publications with CCS and Neurodegenerative Diseases

Organs/Tissues associated with anti-CCS antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >570 publications with CCS and Blood
 Heart Antibodies  >454 publications with CCS and Heart
 Brain Antibodies  >369 publications with CCS and Brain
 Muscle Antibodies  >187 publications with CCS and Muscle
 Liver Antibodies  >168 publications with CCS and Liver
 Bone Antibodies  >137 publications with CCS and Bone
 Kidney Antibodies  >116 publications with CCS and Kidney
 Nerve Antibodies  >116 publications with CCS and Nerve
 Skin Antibodies  >103 publications with CCS and Skin
 Lung Antibodies  >85 publications with CCS and Lung
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