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KLC2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3215498

This is a rabbit polyclonal antibody against KLC2. It was validated on Western BlotTarget Description: Kinesin is a molecular motor that generates ATP-dependent movement of vesicles and organelles along microtubules. Kinesin consists of 2 light chains, such… More details

$490 / 0.1 mL +1 FREE 8GB USB
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Sample Manual Insert View PDF
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
KLC2, Polyclonal Antibody
Full Product Name
KLC2 antibody - C-terminal region
Product Gene Name
Product Synonym Gene Name
FLJ12387
Immunogen Sequence
Synthetic peptide located within the following region: SSEMLVKKLQ GGTPQEPPNP RMKRASSLNF LNKSVEEPTQ PGGTGLSDSR
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rat
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Purity/Purification
Affinity Purified
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Antibody/Peptide Pairs
KLC2 peptide (MBS3240401) is used for blocking the activity of KLC2 antibody (MBS3215498)
Molecular Weight
68kDa
OMIM
611729
3D Structure
ModBase 3D Structure for Q9H0B6
Homology
Cow: 93%; Dog: 93%; Guinea Pig: 86%; Horse: 86%; Human: 100%; Mouse: 86%; Pig: 93%; Rat: 93%
Applications Tested/Suitable for anti-KLC2 antibody
Western Blot (WB)

Western Blot (WB) of anti-KLC2 antibody

WB Suggested Anti-KLC2 Antibody
Titration: 1.0 ug/ml
Positive Control: MCF7 Whole CellKLC2 is supported by BioGPS gene expression data to be expressed in MCF7
Rabbit Anti-KLC2 Polyclonal Antibody – Cat# MBS3215498

Other Notes

Small volumes of anti-KLC2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for KLC2 purchase

MBS3215498 is an antibody targeting KLC2. Also known as KLC2 antibody - C-terminal region. Reactive in Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for KLC2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
kinesin light chain 2 isoform 1
NCBI Official Synonym Full Names
kinesin light chain 2
NCBI Official Symbol
KLC2
UniProt Protein Name
Kinesin light chain 2
Protein Family
UniProt Gene Name
KLC2
UniProt Synonym Gene Names
KLC 2
UniProt Entry Name
KLC2_HUMAN
NCBI Protein Information
kinesin light chain 2

NCBI Summary for KLC2

The protein encoded by this gene is a light chain of kinesin, a molecular motor responsible for moving vesicles and organelles along microtubules. Defects in this gene are a cause of spastic paraplegia, optic atrophy, and neuropathy (SPOAN) syndrome. [provided by RefSeq, Mar 2016]

UniProt Comments for KLC2

KLC2: Kinesin is a microtubule-associated force-producing protein that may play a role in organelle transport. The light chain may function in coupling of cargo to the heavy chain or in the modulation of its ATPase activity. Belongs to the kinesin light chain family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Motor; Microtubule-binding

Chromosomal Location of Human Ortholog: 11q13.2

Cellular Component: ciliary rootlet; microtubule; kinesin complex; neuron projection; protein complex; membrane; cytosol

Molecular Function: protein binding; kinesin binding; microtubule motor activity

Biological Process: metabolic process; axon cargo transport; antigen processing and presentation of exogenous peptide antigen via MHC class II; blood coagulation; microtubule-based movement
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with anti-KLC2 antibody

 Disease Name  Pubmed Publications
 Atrophy Antibodies  >1 publications with KLC2 and Atrophy
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