Rabbit Anti-DCTN3 Polyclonal Antibody – Cat# MBS3215629

WB Suggested Anti-DCTN3 Antibody
Titration: 1.0 ug/ml
Positive Control: 293T Whole CellDCTN3 is supported by BioGPS gene expression data to be expressed in HEK293T

DCTN3 Antibody – Rabbit Polyclonal

Name: DCTN3 Antibody; Polyclonal; Rabbit; MyBioSource
Brand: MyBioSource
SKU: MBS3215629
Price: 490 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3215629

This is a rabbit polyclonal antibody against DCTN3. It was validated on Western BlotTarget Description: This gene encodes the smallest subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to… More details

$490 / 0.1 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

DCTN3, Polyclonal Antibody

Full Product Name

DCTN3 antibody - C-terminal region

Product Gene Name

anti-DCTN3 antibody

Product Synonym Gene Name

DCTN-22; DCTN22; MGC111190

Immunogen Sequence

Synthetic peptide located within the following region: ARLQRLAQIH IQQQDQCVEI TEESKALLEE YNKTTMLLSK QFVQWDELLC

Clonality

Polyclonal

Host

Rabbit

Species Reactivity

Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish

Form/Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Purity/Purification

Affinity Purified

Preparation and Storage

For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Antibody/Peptide Pairs

DCTN3 peptide (MBS3240532) is used for blocking the activity of DCTN3 antibody (MBS3215629)

Molecular Weight

20kDa

OMIM

603161

3D Structure

ModBase 3D Structure for O75355

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 93%; Rabbit: 100%; Rat: 100%; Zebrafish: 79%

Product Categories/Family for anti-DCTN3 antibody

Polyclonal; DNA/RNA/Protein Interactions

Applications Tested/Suitable for anti-DCTN3 antibody

Western Blot (WB)

Other Notes

Small volumes of anti-DCTN3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for DCTN3 purchase

MBS3215629 is an antibody targeting DCTN3. Also known as DCTN3 antibody - C-terminal region. Reactive in Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for DCTN3. It may not necessarily be applicable to this product.

NCBI GI #

166197702

NCBI GeneID

956

NCBI Accession #

NP_001239

UniProt Primary Accession #

O75355

UniProt Related Accession #

O75355

GenBank Nucleotide #

NM_001248

NCBI Official Full Name

ectonucleoside triphosphate diphosphohydrolase 3 isoform 1

NCBI Official Synonym Full Names

ectonucleoside triphosphate diphosphohydrolase 3

NCBI Official Symbol

ENTPD3

NCBI Official Synonym Symbols

HB6; CD39L3; NTPDase-3

UniProt Protein Name

Ectonucleoside triphosphate diphosphohydrolase 3

UniProt Synonym Protein Names

CD39 antigen-like 3; Ecto-ATP diphosphohydrolase 3; Ecto-ATPDase 3; Ecto-ATPase 3; Ecto-apyrase 3; HB6

Protein Family

Dynactin

UniProt Gene Name

ENTPD3

UniProt Synonym Gene Names

CD39L3; NTPDase 3; Ecto-ATPDase 3; Ecto-ATPase 3

UniProt Entry Name

ENTP3_HUMAN

NCBI Protein Information

ectonucleoside triphosphate diphosphohydrolase 3

NCBI Summary for DCTN3

This gene encodes a plasma membrane-bound divalent cation-dependent E-type nucleotidase. The encoded protein is involved in the regulation of extracellular levels of ATP by hydrolysis of it and other nucleotides. Multiple transcript variants have been described. [provided by RefSeq, May 2014]

UniProt Comments for DCTN3

ENTPD3: Has a threefold preference for the hydrolysis of ATP over ADP. Belongs to the GDA1/CD39 NTPase family.

Protein type: EC 3.6.1.5; Hydrolase; Membrane protein, integral; Membrane protein, multi-pass; Nucleotide Metabolism - purine; Nucleotide Metabolism - pyrimidine; Phosphatase (non-protein)

Chromosomal Location of Human Ortholog: 3p21.3

Molecular Function: protein binding

Research Articles on DCTN3

1. NTPDase2 and -3 are ecto-enzymes expressed in the enteric nervous system. Both enzymes confer protection against gut inflammation in experimental colitis and exhibit alterations in Crohn's disease. These observations suggest that purinergic signalling modulated by E-NTPDases governs neuro-immune interactions that are relevant in Crohn's disease.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-DCTN3 antibody

Products by Pathway	Pathway Diagram
Epstein-Barr Virus Infection Pathway antibodies	Epstein-Barr Virus Infection Pathway Diagram
Epstein-Barr Virus Infection Pathway antibodies	Epstein-Barr Virus Infection Pathway Diagram
Purine Metabolism Pathway antibodies	Purine Metabolism Pathway Diagram
Purine Metabolism Pathway antibodies	Purine Metabolism Pathway Diagram
Pyrimidine Metabolism Pathway antibodies	Pyrimidine Metabolism Pathway Diagram
Pyrimidine Metabolism Pathway antibodies	Pyrimidine Metabolism Pathway Diagram

Diseases associated with anti-DCTN3 antibody

Disease Name	Pubmed Publications
Fibrosis Antibodies	>1 publications with DCTN3 and Fibrosis
Inflammation Antibodies	>1 publications with DCTN3 and Inflammation

Organs/Tissues associated with anti-DCTN3 antibody

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>3 publications with DCTN3 and Brain
Nerve Antibodies	>2 publications with DCTN3 and Nerve
Bladder Antibodies	>2 publications with DCTN3 and Bladder
Liver Antibodies	>1 publications with DCTN3 and Liver
Kidney Antibodies	>1 publications with DCTN3 and Kidney
Pancreas Antibodies	>1 publications with DCTN3 and Pancreas