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CD68 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3215841

Target Description: This gene encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily… More details

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Product Overview

Online Datasheet in PDF
Product Name
CD68, Polyclonal Antibody
Full Product Name
CD68 antibody - middle region
Product Gene Name
Product Synonym Gene Name
DKFZp686M18236; GP110; SCARD1; LAMP4
Immunogen Sequence
Synthetic peptide located within the following region: EAWGISVLNP NKTKVQGSCE GAHPHLLLSF PYGHLSFGFM QDLQQKVVYL
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Tested Species Reactivity: Human
Predicted Species Reactivity: Human, Mouse, Rat, Guinea Pig, Pig
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Purity/Purification
Affinity Purified
Concentration
0.5 mg/ml (lot specific)
Preparation and Storage
For short term use, store at 2-8°C. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Antibody/Peptide Pairs
CD68 peptide (MBS3240743) is used for blocking the activity of CD68 antibody (MBS3215841)
Molecular Weight
35kDa
OMIM
153634
3D Structure
ModBase 3D Structure for B4DVT4
Homology
Guinea Pig: 79%; Human: 100%; Mouse: 79%; Pig: 93%; Rat: 93%
Protein Size (# AA)
327 amino acids
Protein Interactions
ADRB2; RALGDS;
Blocking Peptide
For anti-CD68 (MBS3215841) antibody is Catalog # MBS3240743

Product Categories/Family for anti-CD68 antibody

Applications Tested/Suitable for anti-CD68 antibody
Western Blot (WB)

Western Blot (WB) of anti-CD68 antibody

WB Suggested Anti-CD68 Antibody
Titration: 1.0 ug/ml
Positive Control: Jurkat Whole Cell
Rabbit Anti-CD68 Polyclonal Antibody – Cat# MBS3215841

Western Blot (WB) of anti-CD68 antibody

Host: Rabbit
Target: CD68
Positive control (+): Mouse Liver (M-LI)
Negative control (-): Mouse Heart (M-HE)
Antibody concentration: 1ug/ml
Rabbit Anti-CD68 Polyclonal Antibody, Western Blot (WB) – Cat# MBS3215841

Other Notes

Small volumes of anti-CD68 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CD68 purchase

MBS3215841 is an antibody targeting CD68. Also known as CD68 antibody - middle region. Reactive in Tested Species Reactivity: Human
Predicted Species Reactivity: Human, Mouse, Rat, Guinea Pig, Pig. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for CD68. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
macrosialin isoform B
NCBI Official Synonym Full Names
CD68 molecule
NCBI Official Symbol
CD68
NCBI Official Synonym Symbols
GP110; LAMP4; SCARD1
UniProt Protein Name
Macrosialin
UniProt Synonym Protein Names
Gp110; CD_antigen: CD68
Protein Family
UniProt Gene Name
CD68
UniProt Entry Name
CD68_HUMAN
NCBI Protein Information
macrosialin

NCBI Summary for CD68

This gene encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms. [provided by RefSeq, Jul 2008]
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-CD68 antibody

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