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FRMPD2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3217512

This is a rabbit polyclonal antibody against FRMPD2. It was validated on Western BlotTarget Description: This gene encodes a peripheral membrane protein and is located in a region of chromosome 10q that contains a segmental duplication. This copy of the gene… More details

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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
FRMPD2, Polyclonal Antibody
Full Product Name
FRMPD2 Antibody - N-terminal region
Product Gene Name
Immunogen Sequence
Synthetic peptide located within the following region: LLQGQSEDEQ PDASQMHVYS LGMTLYWSAG FHVPPHQPLQ LCEPLHSILL
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Cow, Guinea Pig, Horse, Human, Pig
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Purity/Purification
Affinity Purified
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Antibody/Peptide Pairs
FRMPD2 peptide (MBS3242407) is used for blocking the activity of FRMPD2 antibody (MBS3217512)
Molecular Weight
43kDa
OMIM
613323
3D Structure
ModBase 3D Structure for Q68DX3
Homology
Cow: 79%; Guinea Pig: 79%; Horse: 77%; Human: 100%; Pig: 86%
Immunogen
The immunogen is a synthetic peptide directed towards the N-terminal region of Human FRMPD2
Applications Tested/Suitable for anti-FRMPD2 antibody
Western Blot (WB)

Western Blot (WB) of anti-FRMPD2 antibody

Host: Rabbit
Target Name: FRMPD2
Sample Type: A549 Whole Cell lysates
Antibody Dilution: 1.0ug/ml
Rabbit Anti-FRMPD2 Polyclonal Antibody – Cat# MBS3217512

Other Notes

Small volumes of anti-FRMPD2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for FRMPD2 purchase

MBS3217512 is an antibody targeting FRMPD2. Also known as FRMPD2 Antibody - N-terminal region. Reactive in Cow, Guinea Pig, Horse, Human, Pig. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for FRMPD2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
FERM and PDZ domain-containing protein 2 isoform 3
NCBI Official Synonym Full Names
FERM and PDZ domain containing 2
NCBI Official Symbol
FRMPD2
NCBI Official Synonym Symbols
PDZK4; PDZD5C; PDZK5C
UniProt Protein Name
FERM and PDZ domain-containing protein 2
UniProt Synonym Protein Names
PDZ domain-containing protein 4; PDZ domain-containing protein 5C
UniProt Gene Name
FRMPD2
UniProt Synonym Gene Names
PDZD5C; PDZK4; PDZK5C
UniProt Entry Name
FRPD2_HUMAN
NCBI Protein Information
FERM and PDZ domain-containing protein 2

NCBI Summary for FRMPD2

This gene encodes a peripheral membrane protein and is located in a region of chromosome 10q that contains a segmental duplication. This copy of the gene is full-length and is in the telomeric duplicated region. Two other more centromerically proximal copies of the gene are partial and may represent pseudogenes. This full-length gene appears to function in the establishment and maintenance of cell polarization. The protein is recruited to cell-cell junctions in an E-cadherin-dependent manner, and is selectively localized at the basolateral membrane in polarized epithelial cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2009]
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UniProt Comments for FRMPD2

FRMPD2: May play a role in the regulation of tight junction formation. Binds phosphatidylinositol 3,4-bisphosphate (PtdIns(3,4)P2). 5 isoforms of the human protein are produced by alternative splicing.

Protein type: Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 10q11.22

Cellular Component: tight junction; cytoskeleton; basolateral plasma membrane; cytoplasm

Molecular Function: protein binding; phosphatidylinositol binding
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-FRMPD2 antibody

 Reference Product  PubMed Publications
 ARVCF antibody  >1 publications with FRMPD2 and ARVCF

Diseases associated with anti-FRMPD2 antibody

Organs/Tissues associated with anti-FRMPD2 antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >1 publications with FRMPD2 and Brain
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