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EPS15L1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3217793

This is a rabbit polyclonal antibody against EPS15L1. It was validated on Western BlotTarget Description: EPS15L1 seems to be a constitutive component of clathrin-coated pits that is required for receptor-mediated endocytosis. More details

$490 / 0.1 mL +1 FREE 8GB USB
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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
EPS15L1, Polyclonal Antibody
Full Product Name
EPS15L1 Antibody - C-terminal region
Product Gene Name
Product Synonym Gene Name
EPS15R
Immunogen Sequence
Synthetic peptide located within the following region: GFSDDPFKSK QDTPALPPKK PAPPRPKPPS GKSTPVSQLG SADFPEAPDP
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Purity/Purification
Affinity Purified
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Antibody/Peptide Pairs
EPS15L1 peptide (MBS3242688) is used for blocking the activity of EPS15L1 antibody (MBS3217793)
Molecular Weight
95kDa
3D Structure
ModBase 3D Structure for Q9UBC2
Homology
Dog: 100%; Guinea Pig: 86%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%
Immunogen
The immunogen is a synthetic peptide directed towards the C-terminal region of Human EPS15L1
Applications Tested/Suitable for anti-EPS15L1 antibody
Western Blot (WB)

Western Blot (WB) of anti-EPS15L1 antibody

Host: Rabbit
Target Name: EPS15L1
Sample Type: Placenta lysates
Antibody Dilution: 1.0ug/ml
Rabbit Anti-EPS15L1 Polyclonal Antibody – Cat# MBS3217793

Other Notes

Small volumes of anti-EPS15L1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for EPS15L1 purchase

MBS3217793 is an antibody targeting EPS15L1. Also known as EPS15L1 Antibody - C-terminal region. Reactive in Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for EPS15L1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
epidermal growth factor receptor substrate 15-like 1 isoform 2
NCBI Official Synonym Full Names
epidermal growth factor receptor pathway substrate 15 like 1
NCBI Official Symbol
EPS15L1
NCBI Official Synonym Symbols
EPS15R
UniProt Protein Name
Epidermal growth factor receptor substrate 15-like 1
UniProt Synonym Protein Names
Eps15-related protein
UniProt Gene Name
EPS15L1
UniProt Synonym Gene Names
EPS15R; Eps15R
UniProt Entry Name
EP15R_HUMAN
NCBI Protein Information
epidermal growth factor receptor substrate 15-like 1

UniProt Comments for EPS15L1

EPS15R: epidermal growth factor receptor substrate protein 15R. Contains three EH domains which are implicated in endocytosis, vesicle transport and signal transduction. All three EH domains contain calcium-binding domains ofthe EF-hand type. Contains 2 UIM motifs, which are is responsible for ubiquitin recognition and monoubiquitination. May function as an adaptor between ubiquitinated proteins and the clathrin coat or other endocytic scaffolds.

Protein type: Adaptor/scaffold; Vesicle

Chromosomal Location of Human Ortholog: 19p13.11

Cellular Component: membrane; plasma membrane; coated pit; nucleus

Molecular Function: protein binding; calcium ion binding

Biological Process: negative regulation of epidermal growth factor receptor signaling pathway; epidermal growth factor receptor signaling pathway; endocytosis
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with anti-EPS15L1 antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >1 publications with EPS15L1 and Blood
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