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RGS7BP Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3218312

This is a rabbit polyclonal antibody against RGS7BP. It was validated on Western BlotTarget Description: This gene encodes a protein that binds to all members of the R7 subfamily of regulators of G protein signaling and regulates their translocation between… More details

$490 / 0.1 mL +1 FREE 8GB USB
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Product Overview

Online Datasheet in PDF
Product Name
RGS7BP, Polyclonal Antibody
Full Product Name
RGS7BP Antibody - middle region
Product Gene Name
Product Synonym Gene Name
R7BP
Immunogen Sequence
Synthetic peptide located within the following region: RLYIQLQCCL EMYTTEMLKS ICLLGSLQFH RKGKEPGGGT KSLDCKIEES
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Purity/Purification
Affinity Purified
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Antibody/Peptide Pairs
RGS7BP peptide (MBS3243205) is used for blocking the activity of RGS7BP antibody (MBS3218312)
Molecular Weight
28kDa
OMIM
610890
3D Structure
ModBase 3D Structure for Q6MZT1
Homology
Cow: 93%; Dog: 100%; Guinea Pig: 86%; Horse: 100%; Human: 100%; Mouse: 77%; Pig: 100%; Rabbit: 79%; Rat: 92%
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of Human RGS7BP
Applications Tested/Suitable for anti-RGS7BP antibody
Western Blot (WB)

Western Blot (WB) of anti-RGS7BP antibody

Host: Rabbit
Target Name: RGS7BP
Sample Type: MCF7 Whole Cell lysates
Antibody Dilution: 1.0ug/ml
Rabbit Anti-RGS7BP Polyclonal Antibody – Cat# MBS3218312

Other Notes

Small volumes of anti-RGS7BP antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for RGS7BP purchase

MBS3218312 is an antibody targeting RGS7BP. Also known as RGS7BP Antibody - middle region. Reactive in Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for RGS7BP. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
regulator of G-protein signaling 7-binding protein isoform 1
NCBI Official Synonym Full Names
regulator of G protein signaling 7 binding protein
NCBI Official Symbol
RGS7BP
NCBI Official Synonym Symbols
R7BP
UniProt Protein Name
Regulator of G-protein signaling 7-binding protein
UniProt Synonym Protein Names
R7 family-binding protein
UniProt Gene Name
RGS7BP
UniProt Synonym Gene Names
R7BP
NCBI Protein Information
regulator of G-protein signaling 7-binding protein

NCBI Summary for RGS7BP

This gene encodes a protein that binds to all members of the R7 subfamily of regulators of G protein signaling and regulates their translocation between the nucleus and the plasma membrane. The encoded protein could be regulated by reversible palmitoylation, which anchors it to the plasma membrane. Depalmitoylation localizes the protein to the nucleus. Polymorphisms in this gene may be associated with risk of aspirin-exacerbated respiratory disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2012]
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UniProt Comments for RGS7BP

Regulator of G protein-coupled receptor (GPCR) signaling. Regulatory subunit of the R7-Gbeta5 complexes that acts by controlling the subcellular location of the R7-Gbeta5 complexes. When palmitoylated, it targets the R7-Gbeta5 complexes to the plasma membrane, leading to inhibit G protein alpha subunits. When it is unpalmitoylated, the R7-Gbeta5 complexes undergo a nuclear/cypolasmic shuttling. May also act by controlling the proteolytic stability of R7 proteins, probably by protecting them from degradation.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
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