Rabbit Anti-AZI2 Polyclonal Antibody – Cat# MBS3219670

Host: Rabbit
Target Name: AZI2
Sample Type: 786-0 Whole Cell lysates
Antibody Dilution: 1.0ug/ml

AZI2 Antibody – Rabbit Polyclonal

Name: AZI2 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS3219670
Price: 490 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3219670

This is a rabbit polyclonal antibody against AZI2. It was validated on Western BlotTarget Description: AZI2, or NAP1, contributes to the activation of NFKB-dependent gene expression by activating IKK-related kinases, such as NAK. More details

$490 / 0.1 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

AZI2, Polyclonal Antibody

Full Product Name

AZI2 Antibody - C-terminal region

Product Gene Name

anti-AZI2 antibody

Product Synonym Gene Name

AZI2; NAP1; TBKBP2;

Immunogen Sequence

Synthetic peptide located within the following region: EKLSCDLKIH GLEQELELMR KECSDLKIEL QKAKQTDPYQ EDNLKSRDLQ

Clonality

Polyclonal

Host

Rabbit

Species Reactivity

Human

Form/Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Purity/Purification

Affinity Purified

Preparation and Storage

For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Antibody/Peptide Pairs

AZI2 peptide (MBS3244536) is used for blocking the activity of AZI2 antibody (MBS3219670)

Molecular Weight

26kDa

OMIM

609916

3D Structure

ModBase 3D Structure for Q9H6S1

Immunogen

The immunogen is a synthetic peptide directed towards the C-terminal region of Human AZI2

Product Categories/Family for anti-AZI2 antibody

Polyclonal; Signaling Intermediate

Applications Tested/Suitable for anti-AZI2 antibody

Western Blot (WB)

Other Notes

Small volumes of anti-AZI2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for AZI2 purchase

MBS3219670 is an antibody targeting AZI2. Also known as AZI2 Antibody - C-terminal region. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for AZI2. It may not necessarily be applicable to this product.

NCBI GI #

11968003

NCBI GeneID

64343

NCBI Accession #

NP_071906.1

UniProt Primary Accession #

Q9H6S1

UniProt Related Accession #

Q9H6S1

GenBank Nucleotide #

NM_022461.5

NCBI Official Full Name

5-azacytidine-induced protein 2 isoform a

NCBI Official Synonym Full Names

5-azacytidine induced 2

NCBI Official Symbol

AZI2

NCBI Official Synonym Symbols

AZ2; NAP1; TILP

UniProt Protein Name

5-azacytidine-induced protein 2

UniProt Synonym Protein Names

NF-kappa-B-activating kinase-associated protein 1; Nak-associated protein 1; TILP

Protein Family

5-azacytidine-induced protein

UniProt Gene Name

AZI2

UniProt Synonym Gene Names

NAP1; Nak-associated protein 1

UniProt Entry Name

AZI2_HUMAN

NCBI Protein Information

5-azacytidine-induced protein 2

NCBI Summary for AZI2

AZI2, or NAP1, contributes to the activation of NFKB (see MIM 164011)-dependent gene expression by activating IKK-related kinases, such as NAK (TBK1; MIM 604834) (Fujita et al., 2003 [PubMed 14560022]).[supplied by OMIM, Mar 2008]

UniProt Comments for AZI2

AZI2: Activates serine/threonine-protein kinase TBK1 and facilitates its oligomerization. Enhances the phosphorylation of NF-kappa-B p65 subunit RELA by TBK1. Promotes TBK1-induced as well as TNF-alpha or PMA-induced activation of NF-kappa-B. Participates in IFN-beta promoter activation via TICAM1. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Unknown function

Chromosomal Location of Human Ortholog: 3p24.1

Cellular Component: cytoplasm

Molecular Function: protein binding

Biological Process: tumor necrosis factor production; I-kappaB kinase/NF-kappaB cascade; T cell activation; interleukin-6 production; interferon-gamma production; mitotic cell cycle; interferon-alpha production

Research Articles on AZI2

1. the spatiotemporal mobilization of TICAM-1 in response to dsRNA and the formation of the TICAM-1 speckles containing RIP1 and NAP1 are important for the activation of the TLR3-TICAM-1 pathway.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-AZI2 antibody

Reference Product	PubMed Publications
TBK1 antibody	>2 publications with AZI2 and TBK1
IKBKE antibody	>1 publications with AZI2 and IKBKE

Pathways associated with anti-AZI2 antibody

Products by Pathway	Pathway Diagram
RIG-I-like Receptor Signaling Pathway antibodies	RIG-I-like Receptor Signaling Pathway Diagram
RIG-I-like Receptor Signaling Pathway antibodies	RIG-I-like Receptor Signaling Pathway Diagram
TNF-alpha/NF-kB Signaling Pathway antibodies	TNF-alpha/NF-kB Signaling Pathway Diagram

Organs/Tissues associated with anti-AZI2 antibody

Organ/Tissue Name	Pubmed Publications
Bone Antibodies	>1 publications with AZI2 and Bone
Heart Antibodies	>1 publications with AZI2 and Heart
Bone Marrow Antibodies	>1 publications with AZI2 and Bone Marrow
Muscle Antibodies	>1 publications with AZI2 and Muscle
Embryonic Tissue Antibodies	>1 publications with AZI2 and Embryonic Tissue
Brain Antibodies	>1 publications with AZI2 and Brain