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CCDC6 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3219684

This gene encodes a coiled-coil domain-containing protein. The encoded protein is ubiquitously expressed and may function as a tumor suppressor. A chromosomal rearrangement resulting in the expression of a fusion gene containing a portion of this gene and the… More details

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Product Overview

Online Datasheet in PDF
Product Name
CCDC6, Polyclonal Antibody
Full Product Name
CCDC6 Antibody - C-terminal region
Product Gene Name
Product Synonym Gene Name
H4; PTC; TPC; TST1; D10S170;
Immunogen Sequence
Synthetic peptide located within the following region: HMGTSHGITR PSPRRSNSPD KFKRPTPPPS PNTQTPVQPP PPPPPPPMQP
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 23% sucrose.
Purity/Purification
Affinity purified
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Antibody/Peptide Pairs
CCDC6 peptide (MBS3244549) is used for blocking the activity of CCDC6 antibody (MBS3219684)
Molecular Weight
52 kDa
OMIM
S72869 mRNA
3D Structure
ModBase 3D Structure for Q16204
Immunogen
The immunogen is a synthetic peptide directed towards the C region of human CCDC6
Applications Tested/Suitable for anti-CCDC6 antibody
Western Blot (WB)

Western Blot (WB) of anti-CCDC6 antibody

Host: Rabbit
Target Name: CCDC6
Sample Tissue: Lung Tumor lysates
Antibody Dilution: 1ug/ml
Rabbit Anti-CCDC6 Polyclonal Antibody – Cat# MBS3219684

Other Notes

Small volumes of anti-CCDC6 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CCDC6 purchase

MBS3219684 is an antibody targeting CCDC6. Also known as CCDC6 Antibody - C-terminal region. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for CCDC6. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
coiled-coil domain-containing protein 6
NCBI Official Synonym Full Names
coiled-coil domain containing 6
NCBI Official Symbol
CCDC6
NCBI Official Synonym Symbols
H4; PTC; TPC; TST1; D10S170
UniProt Protein Name
Coiled-coil domain-containing protein 6
UniProt Synonym Protein Names
Papillary thyroid carcinoma-encoded protein; Protein H4
UniProt Gene Name
CCDC6
UniProt Synonym Gene Names
D10S170; TST1
NCBI Protein Information
coiled-coil domain-containing protein 6

UniProt Comments for CCDC6

CCDC6: Defects in CCDC6 are a cause of thyroid papillary carcinoma (TPC). TPC is a common tumor of the thyroid that typically arises as an irregular, solid or cystic mass from otherwise normal thyroid tissue. Papillary carcinomas are malignant neoplasm characterized by the formation of numerous, irregular, finger-like projections of fibrous stroma that is covered with a surface layer of neoplastic epithelial cells. A chromosomal aberration involving CCDC6 is found in thyroid papillary carcinomas. Inversion inv(10)(q11.2;q21) generates the RET/CCDC6 (PTC1) oncogene.

Protein type: Apoptosis; Cytoskeletal; Oncoprotein

Chromosomal Location of Human Ortholog: 10q21.2

Cellular Component: cytoplasm

Molecular Function: protein binding; structural constituent of cytoskeleton

Disease: Thyroid Carcinoma, Papillary
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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