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RPL8 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3219825

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein… More details

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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
RPL8, Polyclonal Antibody
Full Product Name
RPL8 Antibody - middle region
Product Gene Name
anti-RPL8 antibody
Product Synonym Gene Name
L8
Immunogen Sequence
Synthetic peptide located within the following region: NPVEHPFGGG NHQHIGKPST IRRDAPAGRK VGLIAARRTG RLRGTKTVQE
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Purity/Purification
Affinity purified
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Antibody/Peptide Pairs
RPL8 peptide (MBS3244687) is used for blocking the activity of RPL8 antibody (MBS3219825)
Molecular Weight
28 kDa
OMIM
604177
3D Structure
ModBase 3D Structure for P62917
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human RPL8

Product Categories/Family for anti-RPL8 antibody

Polyclonal; RNA Binding Proteins
Applications Tested/Suitable for anti-RPL8 antibody
Western Blot (WB)

Western Blot (WB) of anti-RPL8 antibody

Host: Rabbit
Target Name: RPL8
Sample Tissue: Human Neurofibroma Tumor lysates
Antibody Dilution: 1ug/ml
Rabbit Anti-RPL8 Polyclonal Antibody – Cat# MBS3219825

Other Notes

Small volumes of anti-RPL8 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for RPL8 purchase

MBS3219825 is an antibody targeting RPL8. Also known as RPL8 Antibody - middle region. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for RPL8. It may not necessarily be applicable to this product.

NCBI GI #
4506663
NCBI GeneID
6132
NCBI Accession #
NP_000964.1
UniProt Primary Accession #
P62917
UniProt Related Accession #
P62917
GenBank Nucleotide #
NM_000973.4
NCBI Official Full Name
60S ribosomal protein L8
NCBI Official Synonym Full Names
ribosomal protein L8
NCBI Official Symbol
RPL8
NCBI Official Synonym Symbols
L8
UniProt Protein Name
60S ribosomal protein L8
Protein Family
60S ribosomal protein
UniProt Gene Name
RPL8
UniProt Entry Name
RL8_HUMAN
NCBI Protein Information
60S ribosomal protein L8

UniProt Comments for RPL8

RPL8: a ribosomal protein of the L2P family. Located in the cytoplasm. Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This protein is a component of the 60S subunit. Associates with 5.8S rRNA, very likely participates in the binding of aminoacyl-tRNA, and is a constituent of the elongation factor 2-binding site at the ribosomal subunit interface.

Protein type: Ribosomal; Translation; RNA-binding

Chromosomal Location of Human Ortholog: 8q24.3

Cellular Component: focal adhesion; membrane; cytoplasm; nucleolus; cytosol

Molecular Function: rRNA binding; structural constituent of ribosome; RNA binding

Biological Process: SRP-dependent cotranslational protein targeting to membrane; translational elongation; cellular protein metabolic process; viral reproduction; translation; translational initiation; mRNA catabolic process, nonsense-mediated decay; gene expression; viral transcription; viral infectious cycle; translational termination
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Research Articles on RPL8

1. Report dysregulated expression of RPL8 in disc degeneration.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-RPL8 antibody

 Reference Product  PubMed Publications
 RPL11 antibody  >4 publications with RPL8 and RPL11
 RPS5 antibody  >3 publications with RPL8 and RPS5
 RPS13 antibody  >2 publications with RPL8 and RPS13
 RPL35 antibody  >2 publications with RPL8 and RPL35
 RPS14 antibody  >1 publications with RPL8 and RPS14

Pathways associated with anti-RPL8 antibody

 Products by Pathway  Pathway Diagram
 Cap-dependent Translation Initiation Pathway antibodies  Cap-dependent Translation Initiation Pathway Diagram
 Cytoplasmic Ribosomal Proteins Pathway antibodies  Cytoplasmic Ribosomal Proteins Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 Eukaryotic Translation Elongation Pathway antibodies  Eukaryotic Translation Elongation Pathway Diagram
 Eukaryotic Translation Initiation Pathway antibodies  Eukaryotic Translation Initiation Pathway Diagram
 Eukaryotic Translation Termination Pathway antibodies  Eukaryotic Translation Termination Pathway Diagram
 Formation Of A Pool Of Free 40S Subunits Pathway antibodies  Formation Of A Pool Of Free 40S Subunits Pathway Diagram
 GTP Hydrolysis And Joining Of The 60S Ribosomal Subunit Pathway antibodies  GTP Hydrolysis And Joining Of The 60S Ribosomal Subunit Pathway Diagram
 Gene Expression Pathway antibodies  Gene Expression Pathway Diagram
 Influenza Infection Pathway antibodies  Influenza Infection Pathway Diagram

Diseases associated with anti-RPL8 antibody

 Disease Name  Pubmed Publications
 Anemia Antibodies  >2 publications with RPL8 and Anemia
 Carcinoma Antibodies  >2 publications with RPL8 and Carcinoma
 Necrosis Antibodies  >2 publications with RPL8 and Necrosis
 Congenital Abnormalities Antibodies  >1 publications with RPL8 and Congenital Abnormalities
 Abnormalities, Multiple Antibodies  >1 publications with RPL8 and Abnormalities, Multiple
 Liver Diseases Antibodies  >1 publications with RPL8 and Liver Diseases
 Adenocarcinoma Antibodies  >1 publications with RPL8 and Adenocarcinoma
 Carcinoma, Hepatocellular Antibodies  >1 publications with RPL8 and Carcinoma, Hepatocellular
 Liver Neoplasms Antibodies  >1 publications with RPL8 and Liver Neoplasms

Organs/Tissues associated with anti-RPL8 antibody

 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >5 publications with RPL8 and Liver
 Blood Antibodies  >4 publications with RPL8 and Blood
 Bone Antibodies  >3 publications with RPL8 and Bone
 Brain Antibodies  >3 publications with RPL8 and Brain
 Ovary Antibodies  >2 publications with RPL8 and Ovary
 Muscle Antibodies  >2 publications with RPL8 and Muscle
 Salivary Gland Antibodies  >2 publications with RPL8 and Salivary Gland
 Testis Antibodies  >1 publications with RPL8 and Testis
 Kidney Antibodies  >1 publications with RPL8 and Kidney
 Intestine Antibodies  >1 publications with RPL8 and Intestine
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