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KLC1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3219892

This is a rabbit polyclonal antibody against KLC1. It was validated on Western BlotTarget Description: Conventional kinesin is a tetrameric molecule composed of two heavy chains and two light chains, and transports various cargos along microtubules toward… More details

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Product Overview

Online Datasheet in PDF
Product Name
KLC1, Polyclonal Antibody
Full Product Name
KLC1 Antibody - N-terminal region
Product Gene Name
Product Synonym Gene Name
KLC1; KLC; KNS2;
Immunogen Sequence
Synthetic peptide located within the following region: HLEFMNQLKK YDDDISPSED KDTDSTKEPL DDLFPNDEDD PGQGIQQQHS
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Purity/Purification
Affinity purified
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Antibody/Peptide Pairs
KLC1 peptide (MBS3244747) is used for blocking the activity of KLC1 antibody (MBS3219892)
Molecular Weight
63kDa
OMIM
600025
3D Structure
ModBase 3D Structure for Q07866
Immunogen
The immunogen is a synthetic peptide directed towards the N-terminal region of Human KLC1
Applications Tested/Suitable for anti-KLC1 antibody
Western Blot (WB)

Western Blot (WB) of anti-KLC1 antibody

Host: Rabbit
Target Name: KLC1
Sample Type: MCF7 Whole Cell lysates
Antibody Dilution: 1.0ug/ml
Rabbit Anti-KLC1 Polyclonal Antibody – Cat# MBS3219892

Other Notes

Small volumes of anti-KLC1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for KLC1 purchase

MBS3219892 is an antibody targeting KLC1. Also known as KLC1 Antibody - N-terminal region. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for KLC1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
kinesin light chain 1 isoform 2
NCBI Official Synonym Full Names
kinesin light chain 1
NCBI Official Symbol
KLC1
NCBI Official Synonym Symbols
KLC; KNS2; KNS2A
UniProt Protein Name
Kinesin light chain 1
Protein Family
UniProt Gene Name
KLC1
UniProt Synonym Gene Names
KLC; KNS2
UniProt Entry Name
KLC1_HUMAN
NCBI Protein Information
kinesin light chain 1

NCBI Summary for KLC1

Conventional kinesin is a tetrameric molecule composed of two heavy chains and two light chains, and transports various cargos along microtubules toward their plus ends. The heavy chains provide the motor activity, while the light chains bind to various cargos. This gene encodes a member of the kinesin light chain family. It associates with kinesin heavy chain through an N-terminal domain, and six tetratricopeptide repeat (TPR) motifs are thought to be involved in binding of cargos such as vesicles, mitochondria, and the Golgi complex. Thus, kinesin light chains function as adapter molecules and not motors per se. Although previously named "kinesin 2", this gene is not a member of the kinesin-2 / kinesin heavy chain subfamily of kinesin motor proteins. Extensive alternative splicing produces isoforms with different C-termini that are proposed to bind to different cargos; however, the full-length nature and/or biological validity of most of these variants have not been determined. [provided by RefSeq, Jul 2008]
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UniProt Comments for KLC1

KLC1: a microtubule-associated force-producing protein that may play a role in organelle transport. The light chain may function in coupling of cargo to the heavy chain or in the modulation of its ATPase activity.

Protein type: Microtubule-binding; Motor

Chromosomal Location of Human Ortholog: 14q32.3

Cellular Component: ciliary rootlet; kinesin complex; microtubule; growth cone; membrane; cell soma; axon; cytoplasmic membrane-bound vesicle; cytosol

Molecular Function: tubulin binding; protein binding; motor activity; microtubule motor activity

Biological Process: intracellular protein transport; viral reproduction; metabolic process; axon cargo transport; antigen processing and presentation of exogenous peptide antigen via MHC class II; blood coagulation; microtubule-based movement
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
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