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SMG9 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3222220

Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Is recruited by release factors to stalled ribosomes together with SMG1 and SMG8 (forming the SMG1C protein kinase complex) and, in the SMG1C complex, is required for the… More details

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Sample Manual Insert View PDF
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
SMG9, Polyclonal Antibody
Full Product Name
SMG9 Antibody - N-terminal region
Product Gene Name
Product Synonym Gene Name
C19orf61; F17127_1
Immunogen Sequence
Synthetic peptide located within the following region: ESGHSQPGLY GIERRRRWKE PGSGGPQNLS GPGGRERDYI APWERERRDA
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Purity/Purification
Affinity purified
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Antibody/Peptide Pairs
SMG9 peptide (MBS3246900) is used for blocking the activity of SMG9 antibody (MBS3222220)
Molecular Weight
58 kDa
OMIM
613176
3D Structure
ModBase 3D Structure for Q9H0W8
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human SMG9
Applications Tested/Suitable for anti-SMG9 antibody
Western Blot (WB)

Western Blot (WB) of anti-SMG9 antibody

Host: Rabbit
Target Name: SMG9
Sample Tissue: Human 293T Whole Cell lysates
Antibody Dilution: 1ug/ml
Rabbit Anti-SMG9 Polyclonal Antibody – Cat# MBS3222220

Other Notes

Small volumes of anti-SMG9 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SMG9 purchase

MBS3222220 is an antibody targeting SMG9. Also known as SMG9 Antibody - N-terminal region. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for SMG9. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
protein SMG9
NCBI Official Synonym Full Names
SMG9 nonsense mediated mRNA decay factor
NCBI Official Symbol
SMG9
NCBI Official Synonym Symbols
HBMS; C19orf61; F17127_1
UniProt Protein Name
Protein SMG9
UniProt Synonym Protein Names
Protein smg-9 homolog
Protein Family
UniProt Gene Name
SMG9
UniProt Synonym Gene Names
C19orf61
UniProt Entry Name
SMG9_HUMAN
NCBI Protein Information
protein SMG9

NCBI Summary for SMG9

This gene encodes a regulatory subunit of the SMG1 complex, which plays a critical role in nonsense-mediated mRNA decay (NMD). Binding of the encoded protein to the SMG1 complex kinase scaffold protein results in the inhibition of its kinase activity. Mutations in this gene cause a multiple congenital anomaly syndrome in human patients, characterized by brain malformation, congenital heart disease and other features. [provided by RefSeq, Jul 2016]
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UniProt Comments for SMG9

SMG9: a conserved protein of unknown function.

Protein type: RNA processing

Chromosomal Location of Human Ortholog: 19q13.31

Cellular Component: intracellular; cytosol

Molecular Function: identical protein binding; protein binding

Biological Process: mRNA catabolic process, nonsense-mediated decay; gene expression
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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