Rabbit Anti-USP15 Polyclonal Antibody – Cat# MBS3222511

Host: Rabbit
Target Name: USP15
Sample Tissue: Human Hela Whole Cell lysates
Antibody Dilution: 1ug/ml

USP15 Antibody – Rabbit Polyclonal

Name: USP15 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS3222511
Price: 490 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3222511

This gene encodes a member of the ubiquitin specific protease (USP) family of deubiquitinating enzymes. USP enzymes play critical roles in ubiquitin-dependent processes through polyubiquitin chain disassembly and hydrolysis of ubiquitin-substrate bonds. The… More details

$490 / 0.1 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

USP15, Polyclonal Antibody

Full Product Name

USP15 Antibody - middle region

Product Gene Name

anti-USP15 antibody

Product Synonym Gene Name

UNPH4; UNPH-2

Immunogen Sequence

Synthetic peptide located within the following region: CLPSYTAYKN YDYSEPGRNN EQPGLCGLSN LGNTCFMNSA IQCLSNTPPL

Clonality

Polyclonal

Host

Rabbit

Species Reactivity

Human

Form/Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Purity/Purification

Affinity purified

Preparation and Storage

For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Antibody/Peptide Pairs

USP15 peptide (MBS3247179) is used for blocking the activity of USP15 antibody (MBS3222511)

Molecular Weight

107 kDa

OMIM

604731

3D Structure

ModBase 3D Structure for Q9Y4E8

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human USP15

Product Categories/Family for anti-USP15 antibody

Polyclonal; Signaling Intermediate; Growth Factors & Hormones; E3 & Ubiquitin

Applications Tested/Suitable for anti-USP15 antibody

Western Blot (WB)

Other Notes

Small volumes of anti-USP15 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for USP15 purchase

MBS3222511 is an antibody targeting USP15. Also known as USP15 Antibody - middle region. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for USP15. It may not necessarily be applicable to this product.

NCBI GI #

355330276

NCBI GeneID

9958

NCBI Accession #

NP_001239007.1

UniProt Primary Accession #

Q9Y4E8

UniProt Related Accession #

Q9Y4E8

GenBank Nucleotide #

NM_001252078.1

NCBI Official Full Name

ubiquitin carboxyl-terminal hydrolase 15 isoform 1

NCBI Official Synonym Full Names

ubiquitin specific peptidase 15

NCBI Official Symbol

USP15

NCBI Official Synonym Symbols

UNPH4; UNPH-2

UniProt Protein Name

Ubiquitin carboxyl-terminal hydrolase 15

UniProt Synonym Protein Names

Deubiquitinating enzyme 15; Ubiquitin thioesterase 15; Ubiquitin-specific-processing protease 15; Unph-2; Unph4

UniProt Gene Name

USP15

UniProt Synonym Gene Names

KIAA0529

UniProt Entry Name

UBP15_HUMAN

NCBI Protein Information

ubiquitin carboxyl-terminal hydrolase 15

UniProt Comments for USP15

USP15: Protease that degrades 'Lys-48'-linked polyubiquitin chains. Protects target proteins against proteasomal degradation. Protects APC and human papillomavirus type 16 protein E6 against degradation via the ubiquitin proteasome pathway. Belongs to the peptidase C19 family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Protease; Ubiquitin-specific protease; EC 3.4.19.12; Ubiquitin conjugating system

Chromosomal Location of Human Ortholog: 12q14

Cellular Component: cytoplasm; nucleus

Molecular Function: identical protein binding; protein binding; cysteine-type endopeptidase activity; ubiquitin-specific protease activity; SMAD binding; transforming growth factor beta receptor binding

Biological Process: BMP signaling pathway; proteasomal ubiquitin-dependent protein catabolic process; protein deubiquitination; transforming growth factor beta receptor signaling pathway; negative regulation of transforming growth factor beta receptor signaling pathway

Research Articles on USP15

1. a USP15-dependent lysosomal pathway controls p53-R175H turnover in ovarian cancer cells

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-USP15 antibody

Products by Pathway	Pathway Diagram
Downregulation Of TGF-beta Receptor Signaling Pathway antibodies	Downregulation Of TGF-beta Receptor Signaling Pathway Diagram
Integrated Breast Cancer Pathway antibodies	Integrated Breast Cancer Pathway Diagram
Signal Transduction Pathway antibodies	Signal Transduction Pathway Diagram
Signaling By TGF-beta Receptor Complex Pathway antibodies	Signaling By TGF-beta Receptor Complex Pathway Diagram
TGF-beta Receptor Signaling Activates SMADs Pathway antibodies	TGF-beta Receptor Signaling Activates SMADs Pathway Diagram

Diseases associated with anti-USP15 antibody

Disease Name	Pubmed Publications
Cell Transformation, Neoplastic Antibodies	>1 publications with USP15 and Cell Transformation, Neoplastic
Heart Diseases Antibodies	>1 publications with USP15 and Heart Diseases
Nervous System Diseases Antibodies	>1 publications with USP15 and Nervous System Diseases
Brain Diseases Antibodies	>1 publications with USP15 and Brain Diseases
Hyperplasia Antibodies	>1 publications with USP15 and Hyperplasia

Organs/Tissues associated with anti-USP15 antibody

Organ/Tissue Name	Pubmed Publications
Bone Antibodies	>3 publications with USP15 and Bone
Blood Antibodies	>2 publications with USP15 and Blood
Vascular Antibodies	>2 publications with USP15 and Vascular
Brain Antibodies	>2 publications with USP15 and Brain
Heart Antibodies	>1 publications with USP15 and Heart
Stomach Antibodies	>1 publications with USP15 and Stomach
Muscle Antibodies	>1 publications with USP15 and Muscle
Embryonic Tissue Antibodies	>1 publications with USP15 and Embryonic Tissue