Rabbit Anti-PTPN7 Polyclonal Antibody – Cat# MBS3222655

Host: Rabbit
Target Name: PTPN7
Sample Tissue: Human U937 Whole Cell lysates
Antibody Dilution: 1ug/ml

PTPN7 Antibody – Rabbit Polyclonal

Name: PTPN7 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS3222655
Price: 490 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3222655

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic… More details

$490 / 0.1 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

PTPN7, Polyclonal Antibody

Full Product Name

PTPN7 Antibody - middle region

Product Gene Name

anti-PTPN7 antibody

Product Synonym Gene Name

LPTP; HEPTP; PTPNI; BPTP-4; LC-PTP

Immunogen Sequence

Synthetic peptide located within the following region: ASKDRYKTIL PNPQSRVCLG RAQSQEDGDY INANYIRGYD GKEKVYIATQ

Clonality

Polyclonal

Host

Rabbit

Species Reactivity

Human

Form/Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Purity/Purification

Affinity purified

Preparation and Storage

For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Antibody/Peptide Pairs

PTPN7 peptide (MBS3247322) is used for blocking the activity of PTPN7 antibody (MBS3222655)

Molecular Weight

51 kDa

OMIM

176889

3D Structure

ModBase 3D Structure for P35236

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human PTPN7

Product Categories/Family for anti-PTPN7 antibody

Polyclonal; Cancer; Signal Proteins; Lymphocyte Signaling; Developmental Biology; DNA/RNA/Protein Interactions; Meiosis/Mitosis/Cell Cycle

Applications Tested/Suitable for anti-PTPN7 antibody

Western Blot (WB)

Other Notes

Small volumes of anti-PTPN7 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PTPN7 purchase

MBS3222655 is an antibody targeting PTPN7. Also known as PTPN7 Antibody - middle region. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for PTPN7. It may not necessarily be applicable to this product.

NCBI GI #

315221140

NCBI GeneID

5778

NCBI Accession #

NP_002823.3

UniProt Primary Accession #

P35236

UniProt Related Accession #

P35236

GenBank Nucleotide #

NM_002832.3

NCBI Official Full Name

tyrosine-protein phosphatase non-receptor type 7 isoform 1

NCBI Official Synonym Full Names

protein tyrosine phosphatase non-receptor type 7

NCBI Official Symbol

PTPN7

NCBI Official Synonym Symbols

LPTP; HEPTP; PTPNI; BPTP-4; LC-PTP

UniProt Protein Name

Tyrosine-protein phosphatase non-receptor type 7

UniProt Synonym Protein Names

Hematopoietic protein-tyrosine phosphatase; HEPTP; Protein-tyrosine phosphatase LC-PTP

Protein Family

Tyrosine-protein phosphatase non-receptor

UniProt Gene Name

PTPN7

UniProt Synonym Gene Names

HEPTP

UniProt Entry Name

PTN7_HUMAN

NCBI Protein Information

tyrosine-protein phosphatase non-receptor type 7

UniProt Comments for PTPN7

HePTP: a non-receptor protein-tyrosine phosphatase. Preferentially expressed in a variety of hematopoietic cells, and is an early response gene in lymphokine stimulated cells. Its noncatalytic N-terminus can interact with MAP kinases and suppress the MAP kinase activities. Shown to be involved in the regulation of T cell antigen receptor (TCR) signaling, which was thought to function through dephosphorylating the molecules related to MAP kinase pathway. Three alternatively spliced transcript variants of this gene, which encode two distinct isoforms, are reported. May play a role in the regulation of lymphocyte development.

Protein type: Motility/polarity/chemotaxis; EC 3.1.3.48; Protein phosphatase, tyrosine (non-receptor)

Chromosomal Location of Human Ortholog: 1q32.1

Cellular Component: internal side of plasma membrane; cytoskeleton; cytoplasm; cytosol

Molecular Function: protein binding; protein tyrosine phosphatase activity

Biological Process: protein amino acid dephosphorylation

Research Articles on PTPN7

1. Observational study and genome-wide association study of gene-disease association. (HuGE Navigator)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-PTPN7 antibody

Reference Product	PubMed Publications
MAPK1 antibody	>10 publications with PTPN7 and MAPK1
MAPK3 antibody	>5 publications with PTPN7 and MAPK3
MAPK14 antibody	>3 publications with PTPN7 and MAPK14

Pathways associated with anti-PTPN7 antibody

Products by Pathway	Pathway Diagram
Downstream Signaling In Naive CD8+ T Cells Pathway antibodies	Downstream Signaling In Naive CD8+ T Cells Pathway Diagram
MAPK Signaling Pathway antibodies	MAPK Signaling Pathway Diagram
MAPK Signaling Pathway antibodies	MAPK Signaling Pathway Diagram
MAPK Signaling Pathway antibodies	MAPK Signaling Pathway Diagram
Ras Signaling In The CD4+ TCR Pathway antibodies	Ras Signaling In The CD4+ TCR Pathway Diagram

Diseases associated with anti-PTPN7 antibody

Disease Name	Pubmed Publications
Inflammation Antibodies	>3 publications with PTPN7 and Inflammation
Necrosis Antibodies	>2 publications with PTPN7 and Necrosis
Hematologic Diseases Antibodies	>1 publications with PTPN7 and Hematologic Diseases

Organs/Tissues associated with anti-PTPN7 antibody

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>9 publications with PTPN7 and Blood
Lung Antibodies	>1 publications with PTPN7 and Lung
Kidney Antibodies	>1 publications with PTPN7 and Kidney
Brain Antibodies	>1 publications with PTPN7 and Brain