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DOLPP1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3222983

A similar gene has been characterized in mice and encodes dolichyl pyrophosphate (Dol-P-P) phosphatase. This protein dephosphorylates dolichyl pyrophosphate so that it may be re-utilized as a glycosyl carrier lipid by the oligosaccharyltransferase… More details

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Sample Manual Insert View PDF
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
DOLPP1, Polyclonal Antibody
Full Product Name
DOLPP1 Antibody - C-terminal region
Product Gene Name
anti-DOLPP1 antibody
Product Synonym Gene Name
LSFR2
Immunogen Sequence
Synthetic peptide located within the following region: LTPLFPRIAA WPVSEFFLIR DTSLIPNVLW FEYTVTRAEA RNRQRKLGTK
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Purity/Purification
Affinity purified
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Molecular Weight
22 kDa
OMIM
614516
3D Structure
ModBase 3D Structure for Q86YN1
Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of human DOLPP1

Product Categories/Family for anti-DOLPP1 antibody

Polyclonal; Cell Biology
Applications Tested/Suitable for anti-DOLPP1 antibody
Western Blot (WB)

Western Blot (WB) of anti-DOLPP1 antibody

Host: Rabbit
Target Name: DOLPP1
Sample Tissue: Human Du145 Whole Cell lysates
Antibody Dilution: 1ug/ml
Rabbit Anti-DOLPP1 Polyclonal Antibody – Cat# MBS3222983

Other Notes

Small volumes of anti-DOLPP1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for DOLPP1 purchase

MBS3222983 is an antibody targeting DOLPP1. Also known as DOLPP1 Antibody - C-terminal region. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for DOLPP1. It may not necessarily be applicable to this product.

NCBI GI #
209571523
NCBI GeneID
57171
NCBI Accession #
NP_001129389.1
UniProt Primary Accession #
Q86YN1
UniProt Related Accession #
Q86YN1
GenBank Nucleotide #
NM_001135917.1
NCBI Official Full Name
dolichyldiphosphatase 1 isoform b
NCBI Official Synonym Full Names
dolichyldiphosphatase 1
NCBI Official Symbol
DOLPP1
NCBI Official Synonym Symbols
LSFR2
UniProt Protein Name
Dolichyldiphosphatase 1
UniProt Synonym Protein Names
Dolichyl pyrophosphate phosphatase 1
Protein Family
Dolichyldiphosphatase
UniProt Gene Name
DOLPP1
UniProt Synonym Gene Names
LSFR2
UniProt Entry Name
DOPP1_HUMAN
NCBI Protein Information
dolichyldiphosphatase 1

UniProt Comments for DOLPP1

DOLPP1: Required for efficient N-glycosylation. Necessary for maintaining optimal levels of dolichol-linked oligosaccharides. Hydrolyzes dolichyl pyrophosphate at a very high rate and dolichyl monophosphate at a much lower rate. Does not act on phosphatidate. Belongs to the dolichyldiphosphatase family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Hydrolase; Endoplasmic reticulum; Membrane protein, multi-pass; Membrane protein, integral; Glycan Metabolism - N-glycan biosynthesis; EC 3.6.1.43

Chromosomal Location of Human Ortholog: 9q34.1

Cellular Component: endoplasmic reticulum membrane; integral to endoplasmic reticulum membrane

Molecular Function: dolichyldiphosphatase activity

Biological Process: cellular protein metabolic process; dolichol-linked oligosaccharide biosynthetic process; dolichyl diphosphate biosynthetic process; lipid biosynthetic process; protein amino acid N-linked glycosylation; protein amino acid N-linked glycosylation via asparagine; post-translational protein modification
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-DOLPP1 antibody

 Products by Pathway  Pathway Diagram
 Asparagine N-linked Glycosylation Pathway antibodies  Asparagine N-linked Glycosylation Pathway Diagram
 Biosynthesis Of The N-glycan Precursor (dolichol Lipid-linked Oligosaccharide, LLO) And Transfer To A Nascent Protein Pathway antibodies  Biosynthesis Of The N-glycan Precursor (dolichol Lipid-linked Oligosaccharide, LLO) And Transfer To A Nascent Protein Pathway Diagram
 Metabolism Of Proteins Pathway antibodies  Metabolism Of Proteins Pathway Diagram
 N-Glycan Biosynthesis Pathway antibodies  N-Glycan Biosynthesis Pathway Diagram
 N-Glycan Biosynthesis Pathway antibodies  N-Glycan Biosynthesis Pathway Diagram
 Post-translational Protein Modification Pathway antibodies  Post-translational Protein Modification Pathway Diagram
 Synthesis Of Dolichyl-phosphate Pathway antibodies  Synthesis Of Dolichyl-phosphate Pathway Diagram
 Synthesis Of Substrates In N-glycan Biosythesis Pathway antibodies  Synthesis Of Substrates In N-glycan Biosythesis Pathway Diagram

Organs/Tissues associated with anti-DOLPP1 antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >1 publications with DOLPP1 and Brain
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