Rabbit Anti-POU2F2 Polyclonal Antibody – Cat# MBS3223123

Host: Rabbit
Target Name: POU2F2
Sample Tissue: Human Jurkat Whole Cell lysates
Antibody Dilution: 1ug/ml

POU2F2 Antibody – Rabbit Polyclonal

Name: POU2F2 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS3223123
Price: 490 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3223123

The protein encoded by this gene is a homeobox-containing transcription factor of the POU domain family. The encoded protein binds the octamer sequence 5'-ATTTGCAT-3', a common transcription factor binding site in immunoglobulin gene promoters. Several… More details

$490 / 0.1 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

POU2F2, Polyclonal Antibody

Full Product Name

POU2F2 Antibody - N-terminal region

Product Gene Name

anti-POU2F2 antibody

Product Synonym Gene Name

OCT2; OTF2; Oct-2

Immunogen Sequence

Synthetic peptide located within the following region: SPSEHTDTER NGPDTNHQNP QNKTSPFSVS PTGPSTKIKA EDPSGDSAPA

Clonality

Polyclonal

Host

Rabbit

Species Reactivity

Human

Form/Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Purity/Purification

Affinity purified

Preparation and Storage

For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Antibody/Peptide Pairs

POU2F2 peptide (MBS3247770) is used for blocking the activity of POU2F2 antibody (MBS3223123)

Molecular Weight

66 kDa

OMIM

164176

3D Structure

ModBase 3D Structure for P09086

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human POU2F2

Product Categories/Family for anti-POU2F2 antibody

Polyclonal; Transcription Factor; Transcription Regulation; Immunology

Applications Tested/Suitable for anti-POU2F2 antibody

Western Blot (WB)

Other Notes

Small volumes of anti-POU2F2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for POU2F2 purchase

MBS3223123 is an antibody targeting POU2F2. Also known as POU2F2 Antibody - N-terminal region. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for POU2F2. It may not necessarily be applicable to this product.

NCBI GI #

333360875

NCBI GeneID

5452

NCBI Accession #

NP_001193954.1

UniProt Primary Accession #

P09086

UniProt Related Accession #

P09086

GenBank Nucleotide #

NM_001207025.2

NCBI Official Full Name

POU domain, class 2, transcription factor 2 isoform 1

NCBI Official Synonym Full Names

POU class 2 homeobox 2

NCBI Official Symbol

POU2F2

NCBI Official Synonym Symbols

OCT2; OTF2; Oct-2

UniProt Protein Name

POU domain, class 2, transcription factor 2

UniProt Synonym Protein Names

Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2; Octamer-binding protein 2; Oct-2; Octamer-binding transcription factor 2

Protein Family

POU domain, class 2, transcription factor

UniProt Gene Name

POU2F2

UniProt Synonym Gene Names

OCT2; OTF2; Oct-2; OTF-2

UniProt Entry Name

PO2F2_HUMAN

NCBI Protein Information

POU domain, class 2, transcription factor 2

UniProt Comments for POU2F2

Oct2: Transcription factor that specifically binds to the octamer motif (5'-ATTTGCAT-3'). Regulates transcription in a number of tissues in addition to activating immunoglobulin gene expression. Modulates transcription transactivation by NR3C1, AR and PGR. Isoform 5 activates the U2 small nuclear RNA (snRNA) promoter. Belongs to the POU transcription factor family. Class- 2 subfamily. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: DNA-binding

Chromosomal Location of Human Ortholog: 19q13.2

Cellular Component: cytoplasm; nucleus

Molecular Function: protein domain specific binding; sequence-specific DNA binding; transcription factor activity

Biological Process: transcription from RNA polymerase II promoter; immunoglobulin secretion during immune response; mature B cell differentiation; positive regulation of transcription, DNA-dependent; cell maturation; humoral immune response

Research Articles on POU2F2

1. Identification of novel prostate cancer drivers, ERF, CREB3L1, and POU2F2, using RegNetDriver, a framework for integration of genetic and epigenetic alterations with tissue-specific regulatory network.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-POU2F2 antibody

Reference Product	PubMed Publications
POU2AF1 antibody	>36 publications with POU2F2 and POU2AF1
TBP antibody	>4 publications with POU2F2 and TBP
HMGB2 antibody	>1 publications with POU2F2 and HMGB2

Pathways associated with anti-POU2F2 antibody

Products by Pathway	Pathway Diagram
BCR Signaling Pathway antibodies	BCR Signaling Pathway Diagram
SIDS Susceptibility Pathways antibodies	SIDS Susceptibility Pathways Diagram

Diseases associated with anti-POU2F2 antibody

Disease Name	Pubmed Publications
Neoplasms Antibodies	>43 publications with POU2F2 and Neoplasms
Hematologic Diseases Antibodies	>5 publications with POU2F2 and Hematologic Diseases
Cardiovascular Diseases Antibodies	>4 publications with POU2F2 and Cardiovascular Diseases
Inflammation Antibodies	>3 publications with POU2F2 and Inflammation
Neoplasms, Experimental Antibodies	>3 publications with POU2F2 and Neoplasms, Experimental
Brain Diseases Antibodies	>2 publications with POU2F2 and Brain Diseases
Nervous System Diseases Antibodies	>2 publications with POU2F2 and Nervous System Diseases
Papilloma Antibodies	>1 publications with POU2F2 and Papilloma
Hyperplasia Antibodies	>1 publications with POU2F2 and Hyperplasia

Organs/Tissues associated with anti-POU2F2 antibody

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>115 publications with POU2F2 and Blood
Brain Antibodies	>22 publications with POU2F2 and Brain
Lymph Node Antibodies	>8 publications with POU2F2 and Lymph Node
Lymph Antibodies	>7 publications with POU2F2 and Lymph
Bone Antibodies	>6 publications with POU2F2 and Bone
Embryonic Tissue Antibodies	>3 publications with POU2F2 and Embryonic Tissue
Liver Antibodies	>3 publications with POU2F2 and Liver
Kidney Antibodies	>2 publications with POU2F2 and Kidney
Tonsil Antibodies	>2 publications with POU2F2 and Tonsil
Testis Antibodies	>2 publications with POU2F2 and Testis