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ORC5 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3223291

The origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a… More details

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Product Overview

Online Datasheet in PDF
Product Name
ORC5, Polyclonal Antibody
Full Product Name
ORC5 Antibody - middle region
Product Gene Name
Product Synonym Gene Name
ORC5L; ORC5P; ORC5T; PPP1R117
Immunogen Sequence
Synthetic peptide located within the following region: LKHHGKIKKT NFLKKHEKTS NHLLGPKPFP LDRLLAILYS IVDSRVAPTA
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Purity/Purification
Affinity purified
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Antibody/Peptide Pairs
ORC5 peptide (MBS3247934) is used for blocking the activity of ORC5 antibody (MBS3223291)
Molecular Weight
50 kDa
OMIM
602331
3D Structure
ModBase 3D Structure for O43913
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human ORC5

Product Categories/Family for anti-ORC5 antibody

Applications Tested/Suitable for anti-ORC5 antibody
Western Blot (WB)

Western Blot (WB) of anti-ORC5 antibody

Host: Rabbit
Target Name: ORC5
Sample Tissue: Human 786-0 Whole Cell lysates
Antibody Dilution: 1ug/ml
Rabbit Anti-ORC5 Polyclonal Antibody – Cat# MBS3223291

Other Notes

Small volumes of anti-ORC5 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ORC5 purchase

MBS3223291 is an antibody targeting ORC5. Also known as ORC5 Antibody - middle region. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for ORC5. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
origin recognition complex subunit 5 isoform 1
NCBI Official Synonym Full Names
origin recognition complex subunit 5
NCBI Official Symbol
ORC5
NCBI Official Synonym Symbols
ORC5L; ORC5P; ORC5T; PPP1R117
UniProt Protein Name
Origin recognition complex subunit 5
UniProt Gene Name
ORC5
UniProt Synonym Gene Names
ORC5L
UniProt Entry Name
ORC5_HUMAN
NCBI Protein Information
origin recognition complex subunit 5

UniProt Comments for ORC5

ORC5L: Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. Belongs to the ORC5 family. 2 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 7q22.1

Cellular Component: nucleoplasm; cytoplasm; nuclear origin of replication recognition complex; nucleus; origin recognition complex

Molecular Function: protein binding; nucleotide binding; DNA replication origin binding; ATP binding

Biological Process: DNA replication initiation; mitotic cell cycle; DNA replication; G1/S transition of mitotic cell cycle
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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