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ZPR1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3223336

The protein encoded by this gene is found in the cytoplasm of quiescent cells but translocates to the nucleolus in proliferating cells. The encoded protein interacts with survival motor neuron protein (SMN1) to enhance pre-mRNA splicing and to induce neuronal… More details

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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
ZPR1, Polyclonal Antibody
Full Product Name
ZPR1 Antibody - middle region
Product Gene Name
anti-ZPR1 antibody
Product Synonym Gene Name
ZNF259
Immunogen Sequence
Synthetic peptide located within the following region: FTLIIDDPSG NSFVENPHAP QKDDALVITH YNRTRQQEEM LGLQEEAPAE
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Purity/Purification
Affinity purified
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Antibody/Peptide Pairs
ZPR1 peptide (MBS3247979) is used for blocking the activity of ZPR1 antibody (MBS3223336)
Molecular Weight
50 kDa
OMIM
603901
3D Structure
ModBase 3D Structure for O75312
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human ZNF259

Product Categories/Family for anti-ZPR1 antibody

Polyclonal; Neurobiology; Transcription Regulation; Signaling Intermediate; Developmental Biology; Disease Related; Meiosis/Mitosis/Cell Cycle
Applications Tested/Suitable for anti-ZPR1 antibody
Western Blot (WB)

Western Blot (WB) of anti-ZPR1 antibody

Host: Rabbit
Target Name: ZNF259
Sample Tissue: Human HepG2 Whole Cell lysates
Antibody Dilution: 1ug/ml
Rabbit Anti-ZPR1 Polyclonal Antibody – Cat# MBS3223336

Other Notes

Small volumes of anti-ZPR1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ZPR1 purchase

MBS3223336 is an antibody targeting ZPR1. Also known as ZPR1 Antibody - middle region. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for ZPR1. It may not necessarily be applicable to this product.

NCBI GI #
952556267
NCBI GeneID
8882
NCBI Accession #
NP_001304015.1
UniProt Primary Accession #
O75312
UniProt Related Accession #
O75312
GenBank Nucleotide #
NM_003904.4
NCBI Official Full Name
zinc finger protein ZPR1 isoform 2
NCBI Official Synonym Full Names
ZPR1 zinc finger
NCBI Official Symbol
ZPR1
NCBI Official Synonym Symbols
ZNF259
UniProt Protein Name
Zinc finger protein ZPR1
UniProt Synonym Protein Names
Zinc finger protein 259
Protein Family
Protein
UniProt Gene Name
ZPR1
UniProt Synonym Gene Names
ZNF259
UniProt Entry Name
ZPR1_HUMAN
NCBI Protein Information
zinc finger protein ZPR1

UniProt Comments for ZPR1

ZNF259: May be a signaling molecule that communicates mitogenic signals from the cytoplasm to the nucleus. Binds to the EGF and PDGF receptors. Binds to the elongation factor 1-alpha EF1A. Component of an import snRNP complex composed of KPNB1, SNUPN, SMN1 and ZNF259. Belongs to the ZPR1 family.

Protein type: Nucleolus; Cell cycle regulation

Chromosomal Location of Human Ortholog: 11q23.3

Cellular Component: nucleoplasm; Cajal body; growth cone; cell soma; perinuclear region of cytoplasm; axon; cytoplasm; nucleolus; perikaryon; SMN complex; nucleus

Molecular Function: protein binding; zinc ion binding; translation initiation factor binding; receptor tyrosine kinase binding

Biological Process: cell proliferation; regulation of myelination; trophectodermal cell proliferation; positive regulation of protein import into nucleus; spinal cord development; RNA splicing; DNA endoreduplication; Cajal body organization and biogenesis; microtubule cytoskeleton organization and biogenesis; mRNA processing; signal transduction; positive regulation of RNA splicing; positive regulation of growth; inner cell mass cell proliferation
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Research Articles on ZPR1

1. Results suggest that ZPR1 plays an important role in the etiology of type 2 diabetes mellitus, and this gene might be involved in abnormal glucose metabolism.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-ZPR1 antibody

 Reference Product  PubMed Publications
 SMN1 antibody  >6 publications with ZPR1 and SMN1
 ZNF259 antibody  >6 publications with ZPR1 and ZNF259
 SMN2 antibody  >4 publications with ZPR1 and SMN2
 GEMIN2 antibody  >2 publications with ZPR1 and GEMIN2
 EEF1A2 antibody  >2 publications with ZPR1 and EEF1A2
 GEMIN6 antibody  >1 publications with ZPR1 and GEMIN6
 GEMIN5 antibody  >1 publications with ZPR1 and GEMIN5
 GEMIN7 antibody  >1 publications with ZPR1 and GEMIN7
 EEF1A1 antibody  >1 publications with ZPR1 and EEF1A1

Diseases associated with anti-ZPR1 antibody

 Disease Name  Pubmed Publications
 Nerve Degeneration Antibodies  >4 publications with ZPR1 and Nerve Degeneration
 Disease Models, Animal Antibodies  >1 publications with ZPR1 and Disease Models, Animal
 Dyslipidemias Antibodies  >1 publications with ZPR1 and Dyslipidemias
 Necrosis Antibodies  >1 publications with ZPR1 and Necrosis

Organs/Tissues associated with anti-ZPR1 antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >5 publications with ZPR1 and Blood
 Embryonic Tissue Antibodies  >2 publications with ZPR1 and Embryonic Tissue
 Liver Antibodies  >1 publications with ZPR1 and Liver
 Lung Antibodies  >1 publications with ZPR1 and Lung
 Eye Antibodies  >1 publications with ZPR1 and Eye
 Testis Antibodies  >1 publications with ZPR1 and Testis
 Brain Antibodies  >1 publications with ZPR1 and Brain
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