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PHC2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3223427

In Drosophila melanogaster, the 'Polycomb' group (PcG) of genes are part of a cellular memory system that is responsible for the stable inheritance of gene activity. PcG proteins form a large multimeric, chromatin-associated protein complex. The protein… More details

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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
PHC2, Polyclonal Antibody
Full Product Name
PHC2 Antibody - middle region
Product Gene Name
Product Synonym Gene Name
PH2; EDR2; HPH2
Immunogen Sequence
Synthetic peptide located within the following region: PSSKHLQPQF VIQQQPQPQQ QQPPPQQSRP VLQAEPHPQL ASVSPSVALQ
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Purity/Purification
Affinity purified
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Antibody/Peptide Pairs
PHC2 peptide (MBS3248063) is used for blocking the activity of PHC2 antibody (MBS3223427)
Molecular Weight
91 kDa
OMIM
AJ419231 mRNA
3D Structure
ModBase 3D Structure for Q8IXK0
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human PHC2
Applications Tested/Suitable for anti-PHC2 antibody
Western Blot (WB)

Western Blot (WB) of anti-PHC2 antibody

Host: Rabbit
Target Name: PHC2
Sample Tissue: Human LN18 Whole Cell lysates
Antibody Dilution: 1ug/ml
Rabbit Anti-PHC2 Polyclonal Antibody – Cat# MBS3223427

Other Notes

Small volumes of anti-PHC2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PHC2 purchase

MBS3223427 is an antibody targeting PHC2. Also known as PHC2 Antibody - middle region. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for PHC2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
polyhomeotic-like protein 2 isoform b
NCBI Official Synonym Full Names
polyhomeotic homolog 2
NCBI Official Symbol
PHC2
NCBI Official Synonym Symbols
PH2; EDR2; HPH2
UniProt Protein Name
Polyhomeotic-like protein 2
UniProt Synonym Protein Names
Early development regulatory protein 2
UniProt Gene Name
PHC2
UniProt Synonym Gene Names
EDR2; PH2; hPH2
NCBI Protein Information
polyhomeotic-like protein 2

UniProt Comments for PHC2

PHC2: Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: Transcription, coactivator/corepressor

Chromosomal Location of Human Ortholog: 1p35.1

Cellular Component: heterochromatin; nucleoplasm; nucleus; PcG protein complex

Molecular Function: DNA binding; identical protein binding; protein binding; zinc ion binding

Biological Process: multicellular organism development; spermatogenesis
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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