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SRM Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3223566

Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM). Has a strong preference for putrescine as substrate, and has very low activity towards 1,3-diaminopropane. Has extremely low activity towards spermidine… More details

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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
SRM, Polyclonal Antibody
Full Product Name
SRM Antibody - middle region
Product Gene Name
anti-SRM antibody
Product Synonym Gene Name
SpdST; SpdSy; AA407669
Immunogen Sequence
Synthetic peptide located within the following region: MKQNQDAFDV IITDSSDPMG PAESLFKESY YQLMKTALKE DGILCCQGEC
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Mouse
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Purity/Purification
Affinity purified
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Antibody/Peptide Pairs
SRM peptide (MBS3248181) is used for blocking the activity of SRM antibody (MBS3223566)
Molecular Weight
34 kDa
3D Structure
ModBase 3D Structure for Q64674
Immunogen
The immunogen is a synthetic peptide directed towards the middle terminal region of mouse SRM

Product Categories/Family for anti-SRM antibody

Polyclonal; Cell Biology
Applications Tested/Suitable for anti-SRM antibody
Western Blot (WB)

Western Blot (WB) of anti-SRM antibody

Host: Rabbit
Target Name: SRM
Sample Tissue: Mouse Testis lysates
Antibody Dilution: 1ug/ml
Rabbit Anti-SRM Polyclonal Antibody – Cat# MBS3223566

Other Notes

Small volumes of anti-SRM antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SRM purchase

MBS3223566 is an antibody targeting SRM. Also known as SRM Antibody - middle region. Reactive in Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for SRM. It may not necessarily be applicable to this product.

NCBI GI #
6678131
NCBI GeneID
20810
NCBI Accession #
NP_033298.1
UniProt Primary Accession #
Q64674
UniProt Related Accession #
Q64674
GenBank Nucleotide #
NM_009272.4
NCBI Official Full Name
spermidine synthase
NCBI Official Synonym Full Names
spermidine synthase
NCBI Official Symbol
Srm
NCBI Official Synonym Symbols
SpdST; SpdSy; AA407669
UniProt Protein Name
Spermidine synthase
UniProt Synonym Protein Names
Putrescine aminopropyltransferase
UniProt Gene Name
Srm
UniProt Synonym Gene Names
SPDSY
NCBI Protein Information
spermidine synthase

UniProt Comments for SRM

SRM: Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM). Has a strong preference for putrescine as substrate, and has very low activity towards 1,3-diaminopropane. Has extremely low activity towards spermidine. Belongs to the spermidine/spermine synthase family.

Protein type: Amino Acid Metabolism - arginine and proline; Amino Acid Metabolism - cysteine and methionine; EC 2.5.1.16; Other Amino Acids Metabolism - beta-alanine; Other Amino Acids Metabolism - glutathione; Transferase

Chromosomal Location of Human Ortholog: 4|4 E2

Molecular Function: catalytic activity; identical protein binding; protein homodimerization activity; spermidine synthase activity; transferase activity

Biological Process: polyamine biosynthetic process; polyamine metabolic process; spermidine biosynthetic process
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Research Articles on SRM

1. results indicate that SpdS levels are not rate limiting in vivo for polyamine biosynthesis and are unlikely to exert significant regulatory effects on cellular polyamine content and function

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-SRM antibody

 Products by Pathway  Pathway Diagram
 Arginine And Proline Metabolism Pathway antibodies  Arginine And Proline Metabolism Pathway Diagram
 Arginine And Proline Metabolism Pathway antibodies  Arginine And Proline Metabolism Pathway Diagram
 Cysteine And Methionine Metabolism Pathway antibodies  Cysteine And Methionine Metabolism Pathway Diagram
 Cysteine And Methionine Metabolism Pathway antibodies  Cysteine And Methionine Metabolism Pathway Diagram
 Glutathione Metabolism Pathway antibodies  Glutathione Metabolism Pathway Diagram
 Glutathione Metabolism Pathway antibodies  Glutathione Metabolism Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Amino Acids And Derivatives Pathway antibodies  Metabolism Of Amino Acids And Derivatives Pathway Diagram
 Metabolism Of Polyamines Pathway antibodies  Metabolism Of Polyamines Pathway Diagram
 Methionine Salvage Pathway antibodies  Methionine Salvage Pathway Diagram

Diseases associated with anti-SRM antibody

 Disease Name  Pubmed Publications
 Pain Antibodies  >138 publications with SRM and Pain
 Brain Diseases Antibodies  >60 publications with SRM and Brain Diseases
 Drug Toxicity Antibodies  >53 publications with SRM and Drug Toxicity
 Autoimmune Diseases Antibodies  >45 publications with SRM and Autoimmune Diseases
 Carcinoma Antibodies  >39 publications with SRM and Carcinoma
 Inflammation Antibodies  >27 publications with SRM and Inflammation
 Necrosis Antibodies  >25 publications with SRM and Necrosis
 Kidney Diseases Antibodies  >24 publications with SRM and Kidney Diseases
 Fibrosis Antibodies  >21 publications with SRM and Fibrosis
 Neuromuscular Diseases Antibodies  >21 publications with SRM and Neuromuscular Diseases

Organs/Tissues associated with anti-SRM antibody

 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >133 publications with SRM and Liver
 Muscle Antibodies  >107 publications with SRM and Muscle
 Bone Antibodies  >75 publications with SRM and Bone
 Brain Antibodies  >57 publications with SRM and Brain
 Heart Antibodies  >52 publications with SRM and Heart
 Lung Antibodies  >52 publications with SRM and Lung
 Skin Antibodies  >27 publications with SRM and Skin
 Eye Antibodies  >27 publications with SRM and Eye
 Connective Tissue Antibodies  >24 publications with SRM and Connective Tissue
 Thymus Antibodies  >17 publications with SRM and Thymus
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