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FAAH Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3223619

catalyzes the degradation and signal termination of the endocannabinoid class of signalling lipids. More details

$490 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
FAAH, Polyclonal Antibody
Full Product Name
FAAH Antibody - middle region
Product Gene Name
anti-FAAH antibody
Immunogen Sequence
Synthetic peptide located within the following region: PLGLGTDIGG SIRFPSAFCG ICGLKPTGNR LSKSGLKGCV YGQTAVQLSL
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Rat
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Purity/Purification
Affinity purified
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Molecular Weight
63 kDa
3D Structure
ModBase 3D Structure for P97612
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of rat FAAH

Product Categories/Family for anti-FAAH antibody

Polyclonal; Signaling Intermediate; Signal Transduction; Apoptosis
Applications Tested/Suitable for anti-FAAH antibody
Western Blot (WB)

Western Blot (WB) of anti-FAAH antibody

Host: Rabbit
Target Name: FAAH
Sample Tissue: Rat Thymus lysates
Antibody Dilution: 1ug/ml
Rabbit Anti-FAAH Polyclonal Antibody – Cat# MBS3223619

Other Notes

Small volumes of anti-FAAH antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for FAAH purchase

MBS3223619 is an antibody targeting FAAH. Also known as FAAH Antibody - middle region. Reactive in Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for FAAH. It may not necessarily be applicable to this product.

NCBI GI #
13162304
NCBI GeneID
29347
NCBI Accession #
NP_077046.1
UniProt Primary Accession #
P97612
UniProt Related Accession #
P97612
GenBank Nucleotide #
NM_024132.3
NCBI Official Full Name
fatty-acid amide hydrolase 1
NCBI Official Synonym Full Names
fatty acid amide hydrolase
NCBI Official Symbol
Faah
UniProt Protein Name
Fatty-acid amide hydrolase 1
UniProt Synonym Protein Names
Anandamide amidohydrolase 1; Oleamide hydrolase 1
Protein Family
Fatty acid amide hydrolase
UniProt Gene Name
Faah
UniProt Synonym Gene Names
Faah1
UniProt Entry Name
FAAH1_RAT
NCBI Protein Information
fatty-acid amide hydrolase 1

NCBI Summary for FAAH

catalyzes the degradation and signal termination of the endocannabinoid class of signalling lipids [RGD, Feb 2006]

UniProt Comments for FAAH

FAAH: Degrades bioactive fatty acid amides like oleamide, the endogenous cannabinoid, anandamide and myristic amide to their corresponding acids, thereby serving to terminate the signaling functions of these molecules. Hydrolyzes polyunsaturated substrate anandamide preferentially as compared to monounsaturated substrates. Homodimer. Highly expressed in the brain, small intestine, pancreas, skeletal muscle and testis. Also expressed in the kidney, liver, lung, placenta and prostate. Inhibited by O-aryl carbamates and alpha-keto heterocytes. Belongs to the amidase family.

Protein type: EC 3.5.1.99; Hydrolase; Membrane protein, integral

Cellular Component: Golgi membrane; endoplasmic reticulum membrane; integral to membrane

Molecular Function: protein homodimerization activity; amidase activity; carbon-nitrogen ligase activity, with glutamine as amido-N-donor; fatty acid amide hydrolase activity; phospholipid binding; acylglycerol lipase activity; hydrolase activity, acting on ester bonds; lipid binding

Biological Process: fatty acid catabolic process; fatty acid metabolic process
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Research Articles on FAAH

1. Study examined the effect of URB597, a selective FAAH inhibitor, on neuroinflammation, physiological and behavioural alterations following administration of the TLR3 agonist and viral mimetic poly I:C to female rats. URB597 attenuated TLR3-mediated fever, mechanical and cold allodynia, and anxiety-like behaviour in the elevated plus maze and open field arena; attenuated TLR3-mediated increase in CD11b and CD68 expression.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-FAAH antibody

 Reference Product  PubMed Publications
 Mgll antibody  >11 publications with FAAH and Mgll
 Napepld antibody  >5 publications with FAAH and Napepld
 Lep antibody  >1 publications with FAAH and Lep
 Ppara antibody  >1 publications with FAAH and Ppara

Pathways associated with anti-FAAH antibody

 Products by Pathway  Pathway Diagram
 Retrograde Endocannabinoid Signaling Pathway antibodies  Retrograde Endocannabinoid Signaling Pathway Diagram
 Retrograde Endocannabinoid Signaling Pathway antibodies  Retrograde Endocannabinoid Signaling Pathway Diagram

Diseases associated with anti-FAAH antibody

 Disease Name  Pubmed Publications
 Pain Antibodies  >206 publications with FAAH and Pain
 Nervous System Diseases Antibodies  >161 publications with FAAH and Nervous System Diseases
 Inflammation Antibodies  >99 publications with FAAH and Inflammation
 Fatty Liver Antibodies  >55 publications with FAAH and Fatty Liver
 Obesity Antibodies  >54 publications with FAAH and Obesity
 Substance-Related Disorders Antibodies  >46 publications with FAAH and Substance-Related Disorders
 Death Antibodies  >27 publications with FAAH and Death
 Hypothermia Antibodies  >24 publications with FAAH and Hypothermia
 Necrosis Antibodies  >19 publications with FAAH and Necrosis
 Cardiovascular Diseases Antibodies  >16 publications with FAAH and Cardiovascular Diseases

Organs/Tissues associated with anti-FAAH antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >424 publications with FAAH and Brain
 Liver Antibodies  >55 publications with FAAH and Liver
 Connective Tissue Antibodies  >21 publications with FAAH and Connective Tissue
 Heart Antibodies  >21 publications with FAAH and Heart
 Colon Antibodies  >17 publications with FAAH and Colon
 Placenta Antibodies  >16 publications with FAAH and Placenta
 Prostate Antibodies  >11 publications with FAAH and Prostate
 Testis Antibodies  >11 publications with FAAH and Testis
 Pancreas Antibodies  >8 publications with FAAH and Pancreas
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