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C3AR1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3224244

C3a is an anaphylatoxin released during activation of the complement system. The protein encoded by this gene is an orphan G protein-coupled receptor for C3a. Binding of C3a by the encoded receptor activates chemotaxis, granule enzyme release, superoxide… More details

$490 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
C3AR1, Polyclonal Antibody
Full Product Name
C3AR1 Antibody - C-terminal region
Product Gene Name
anti-C3AR1 antibody
Product Synonym Gene Name
AZ3B; C3AR; HNFAG09
Immunogen Sequence
Synthetic peptide located within the following region: FNPFLYALLG KDFRKKARQS IQGILEAAFS EELTRSTHCP SNNVISERNS
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Purity/Purification
Affinity purified
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Antibody/Peptide Pairs
C3AR1 peptide (MBS3248558) is used for blocking the activity of C3AR1 antibody (MBS3224244)
Molecular Weight
53 kDa
OMIM
605246
3D Structure
ModBase 3D Structure for Q16581
Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of human C3AR1

Product Categories/Family for anti-C3AR1 antibody

Polyclonal; Signaling Intermediate; Disease Related
Applications Tested/Suitable for anti-C3AR1 antibody
Western Blot (WB)

Western Blot (WB) of anti-C3AR1 antibody

Host: Rabbit
Target Name: C3AR1
Sample Tissue: Human OVCAR-3 Whole Cell lysates
Antibody Dilution: 1ug/ml
Rabbit Anti-C3AR1 Polyclonal Antibody – Cat# MBS3224244

Other Notes

Small volumes of anti-C3AR1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for C3AR1 purchase

MBS3224244 is an antibody targeting C3AR1. Also known as C3AR1 Antibody - C-terminal region. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for C3AR1. It may not necessarily be applicable to this product.

NCBI GI #
1029201565
NCBI GeneID
719
NCBI Accession #
NP_001313404.1
UniProt Primary Accession #
Q16581
UniProt Related Accession #
Q16581
GenBank Nucleotide #
NM_001326475.1
NCBI Official Full Name
C3a anaphylatoxin chemotactic receptor
NCBI Official Synonym Full Names
complement C3a receptor 1
NCBI Official Symbol
C3AR1
NCBI Official Synonym Symbols
AZ3B; C3AR; HNFAG09
UniProt Protein Name
C3a anaphylatoxin chemotactic receptor
Protein Family
C3a anaphylatoxin chemotactic receptor
UniProt Gene Name
C3AR1
UniProt Synonym Gene Names
AZ3B; C3R1; HNFAG09; C3AR; C3a-R
UniProt Entry Name
C3AR_HUMAN
NCBI Protein Information
C3a anaphylatoxin chemotactic receptor

UniProt Comments for C3AR1

C3aR: Receptor for the chemotactic and inflammatory peptide anaphylatoxin C3a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production. Belongs to the G-protein coupled receptor 1 family.

Protein type: GPCR, family 1; Receptor, GPCR; Membrane protein, multi-pass; Membrane protein, integral

Chromosomal Location of Human Ortholog: 12p13.31

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: G-protein coupled receptor activity; C3a anaphylatoxin receptor activity; complement component C3a receptor activity; phosphoinositide phospholipase C activity

Biological Process: G-protein coupled receptor protein signaling pathway; positive regulation of angiogenesis; elevation of cytosolic calcium ion concentration; blood circulation; metabolic process; complement receptor mediated signaling pathway; inflammatory response; chemotaxis
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Research Articles on C3AR1

1. C3aR-positive cells are found more often in patients with inflammatory cardiomyopathy. The relevance of C3aR-positive cells in patients with non-ischaemic cardiomyopathy should be further evaluated as potential predictors or modulators of adverse cardiac remodelling, the substrate of progressive heart failure.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
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