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HTR4 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3224472

This is a rabbit polyclonal antibody against HTR4. It was validated on Western Blot using a cell lysate as a positive control.Target Description: HTR4 is a member of the family of serotonin receptors, which are G protein coupled receptors that stimulate cAMP… More details

$490 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
HTR4, Polyclonal Antibody
Full Product Name
HTR4 antibody - middle region
Product Gene Name
Product Synonym Gene Name
5-HT4; 5-HT4R
Immunogen Sequence
Synthetic peptide located within the following region: GCWVIPTFIS FLPIMQGWNN IGIIDLIEKR KFNQNSNSTY CVFMVNKPYA
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Cow, Dog, Horse, Human, Pig, Rabbit, Rat
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Purity/Purification
Affinity Purified
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Antibody/Peptide Pairs
HTR4 peptide (MBS3225136) is used for blocking the activity of HTR4 antibody (MBS3224472)
Molecular Weight
44kDa
OMIM
602164
3D Structure
ModBase 3D Structure for Q13639
Homology
Cow: 88%; Dog: 100%; Horse: 93%; Human: 100%; Pig: 93%; Rabbit: 100%; Rat: 86%
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human HTR4
Applications Tested/Suitable for anti-HTR4 antibody
Western Blot (WB)

Western Blot (WB) of anti-HTR4 antibody

WB Suggested Anti-HTR4 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:2500
Positive Control: HepG2 cell lysate
Rabbit Anti-HTR4 Polyclonal Antibody – Cat# MBS3224472

Other Notes

Small volumes of anti-HTR4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for HTR4 purchase

MBS3224472 is an antibody targeting HTR4. Also known as HTR4 antibody - middle region. Reactive in Cow, Dog, Horse, Human, Pig, Rabbit, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for HTR4. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
5-hydroxytryptamine receptor 4 isoform b
NCBI Official Synonym Full Names
5-hydroxytryptamine receptor 4
NCBI Official Symbol
HTR4
NCBI Official Synonym Symbols
5-HT4; 5-HT4R
UniProt Protein Name
5-hydroxytryptamine receptor 4
UniProt Synonym Protein Names
Serotonin receptor 4
UniProt Gene Name
HTR4
UniProt Synonym Gene Names
5-HT-4; 5-HT4
UniProt Entry Name
5HT4R_HUMAN
NCBI Protein Information
5-hydroxytryptamine receptor 4

NCBI Summary for HTR4

This gene is a member of the family of serotonin receptors, which are G protein coupled receptors that stimulate cAMP production in response to serotonin (5-hydroxytryptamine). The gene product is a glycosylated transmembrane protein that functions in both the peripheral and central nervous system to modulate the release of various neurotransmitters. Multiple transcript variants encoding proteins with distinct C-terminal sequences have been described. [provided by RefSeq, May 2010]
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UniProt Comments for HTR4

5-HT(4): This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase. Belongs to the G-protein coupled receptor 1 family. 8 isoforms of the human protein are produced by alternative splicing.

Protein type: Receptor, GPCR; GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 5q31-q33

Cellular Component: membrane; integral to plasma membrane; cytoplasm; plasma membrane; endosome

Molecular Function: serotonin receptor activity

Biological Process: synaptic transmission; G-protein coupled receptor protein signaling pathway; G-protein signaling, coupled to cyclic nucleotide second messenger; positive regulation of cell proliferation; regulation of appetite; serotonin receptor signaling pathway
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-HTR4 antibody

 Reference Product  PubMed Publications
 ADRB2 antibody  >1 publications with HTR4 and ADRB2

Organs/Tissues associated with anti-HTR4 antibody

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