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GDI2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3224491

This is a rabbit polyclonal antibody against GDI2. It was validated on Western Blot using a cell lysate as a positive control.Target Description: GDP dissociation inhibitors are proteins that regulate the GDP-GTP exchange reaction of members of the rab… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
GDI2, Polyclonal Antibody
Full Product Name
GDI2 antibody - C-terminal region
Product Gene Name
Product Synonym Gene Name
RABGDIB
Immunogen Sequence
Synthetic peptide located within the following region: EPEKEIRPAL ELLEPIEQKF VSISDLLVPK DLGTESQIFI SRTYDATTHF
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Guinea Pig, Horse, Human, Mouse, Sheep
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Purity/Purification
Affinity Purified
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Antibody/Peptide Pairs
GDI2 peptide (MBS3225123) is used for blocking the activity of GDI2 antibody (MBS3224491)
Molecular Weight
51kDa
OMIM
D13988 mRNA
3D Structure
ModBase 3D Structure for P50395
Homology
Guinea Pig: 92%; Horse: 100%; Human: 100%; Mouse: 92%; Sheep: 100%
Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of human GDI2
Applications Tested/Suitable for anti-GDI2 antibody
Western Blot (WB)

Western Blot (WB) of anti-GDI2 antibody

Host: Rabbit
Target Name: GDI2
Sample Tissue: Human Fetal Lung
Antibody Dilution: 1.0ug/ml
Rabbit Anti-GDI2 Polyclonal Antibody – Cat# MBS3224491

Western Blot (WB) of anti-GDI2 antibody

WB Suggested Anti-GDI2 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: HepG2 cell lysateGDI2 is strongly supported by BioGPS gene expression data to be expressed in Human HepG2 cells
Rabbit Anti-GDI2 Polyclonal Antibody, Western Blot (WB) – Cat# MBS3224491

Other Notes

Small volumes of anti-GDI2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GDI2 purchase

MBS3224491 is an antibody targeting GDI2. Also known as GDI2 antibody - C-terminal region. Reactive in Guinea Pig, Horse, Human, Mouse, Sheep. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for GDI2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
rab GDP dissociation inhibitor beta isoform 1
NCBI Official Synonym Full Names
GDP dissociation inhibitor 2
NCBI Official Symbol
GDI2
NCBI Official Synonym Symbols
RABGDIB; HEL-S-46e
UniProt Protein Name
Rab GDP dissociation inhibitor beta
UniProt Synonym Protein Names
Guanosine diphosphate dissociation inhibitor 2; GDI-2
UniProt Gene Name
GDI2
UniProt Synonym Gene Names
RABGDIB; Rab GDI beta; GDI-2
NCBI Protein Information
rab GDP dissociation inhibitor beta

NCBI Summary for GDI2

GDP dissociation inhibitors are proteins that regulate the GDP-GTP exchange reaction of members of the rab family, small GTP-binding proteins of the ras superfamily, that are involved in vesicular trafficking of molecules between cellular organelles. GDIs slow the rate of dissociation of GDP from rab proteins and release GDP from membrane-bound rabs. GDI2 is ubiquitously expressed. The GDI2 gene contains many repetitive elements indicating that it may be prone to inversion/deletion rearrangements. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]
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UniProt Comments for GDI2

Regulates the GDP/GTP exchange reaction of most Rab proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-GDI2 antibody

 Reference Product  PubMed Publications
 ARHGDIB antibody  >1 publications with GDI2 and ARHGDIB
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