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GABPB1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3224673

This is a rabbit polyclonal antibody against GABPB2. It was validated on Western Blot using a cell lysate as a positive control.Target Description: GABPB2 encodes the GA-binding protein transcription factor, beta subunit. This protein forms a tetrameric… More details

$440 / 0.1 mL +1 FREE 8GB USB
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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
GABPB2 (GABPB1), Polyclonal Antibody
Full Product Name
GABPB2 antibody - C-terminal region
Product Gene Name
Product Synonym Gene Name
E4TF1; GABPB; BABPB2; E4TF1B; GABPB2; NRF2B1; NRF2B2; E4TF1-47; E4TF1-53
Immunogen Sequence
Synthetic peptide located within the following region: PDGQQVLTVP ATDIAEETVI SEEPPAKRQC IEIIENRVES AEIEEREALQ
Clonality
Polyclonal
Host
Rabbit
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Purity/Purification
Protein A purified
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Antibody/Peptide Pairs
GABPB2 peptide (MBS3225404) is used for blocking the activity of GABPB2 antibody (MBS3224673)
Molecular Weight
42kDa
OMIM
600610
3D Structure
ModBase 3D Structure for Q06547
Homology
Chicken: 92%
Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of human GABPB2
Applications Tested/Suitable for anti-GABPB1 antibody
Western Blot (WB)

Western Blot (WB) of anti-GABPB1 antibody

WB Suggested Antibody Titration: 1.25 ug/ml
Positive Control: HepG2GABPB1 is supported by BioGPS gene expression data to be expressed in HepG2
Rabbit Anti-GABPB1 Polyclonal Antibody – Cat# MBS3224673

Other Notes

Small volumes of anti-GABPB1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GABPB1 purchase

MBS3224673 is an antibody targeting GABPB1. Also known as GABPB2 antibody - C-terminal region. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for GABPB1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
GA-binding protein subunit beta-1 isoform beta 1
NCBI Official Synonym Full Names
GA binding protein transcription factor subunit beta 1
NCBI Official Symbol
GABPB1
NCBI Official Synonym Symbols
E4TF1; GABPB; BABPB2; E4TF1B; GABPB2; NRF2B1; NRF2B2; GABPB-1; E4TF1-47; E4TF1-53
UniProt Protein Name
GA-binding protein subunit beta-1
UniProt Synonym Protein Names
GABP subunit beta-2; GABPB-2; Nuclear respiratory factor 2; Transcription factor E4TF1-47; Transcription factor E4TF1-53
Protein Family
UniProt Gene Name
GABPB1
UniProt Synonym Gene Names
E4TF1B; GABPB; GABPB2; GABP subunit beta-1; GABPB-1; GABPB-2
UniProt Entry Name
GABP1_HUMAN
NCBI Protein Information
GA-binding protein subunit beta-1

NCBI Summary for GABPB1

This gene encodes the GA-binding protein transcription factor, beta subunit. This protein forms a tetrameric complex with the alpha subunit, and stimulates transcription of target genes. The encoded protein may be involved in activation of cytochrome oxidase expression and nuclear control of mitochondrial function. The crystal structure of a similar protein in mouse has been resolved as a ternary protein complex. Multiple transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
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UniProt Comments for GABPB1

GABPB1: Transcription factor capable of interacting with purine rich repeats (GA repeats). Necessary for the expression of the Adenovirus E4 gene. 4 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 15q21.2

Cellular Component: nucleoplasm; nucleus

Molecular Function: protein binding; protein heterodimerization activity; transcription factor activity

Biological Process: regulation of transcription from RNA polymerase II promoter; mitochondrion organization and biogenesis; transcription, DNA-dependent; organelle organization and biogenesis; positive regulation of transcription from RNA polymerase II promoter
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-GABPB1 antibody

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