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CXADR Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3249886

Description of Target: This gene encodes a protein that is part of the Cortical Thymocyte marker in Xenopus (CTX) subfamily within the immunoglobulin superfamily. Members of this subfamily, predominantly expressed on the surface of endothelial and epithelial… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CXADR, Polyclonal Antibody
Full Product Name
CXADR Antibody-middle region
Product Gene Name
Product Synonym Names
coxsackievirus and adenovirus receptor homolog; CAR; MCAR; MCVADR; AU016810; AW553441; 2610206D03Rik
Immunogen Sequence
RSYIGSNHSS LGSMSPSNME GYSKTQYNQV PSEDFERAPQ SPTLAPAKVA
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Mouse
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Purity/Purification
Affinity Purified
Concentration
Batch dependent within range: 100ul at 0.5-1mg/ml (lot specific)
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Antibody/Peptide Pairs
CXADR peptide (MBS3249560) is used for blocking the activity of CXADR antibody (MBS3249886)
Molecular Weight
38kDa
3D Structure
ModBase 3D Structure for P97792
Protein Size
352 amino acids
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of mouse CXADR
Applications Tested/Suitable for anti-CXADR antibody
Western Blot (WB)

Western Blot (WB) of anti-CXADR antibody

Host: Rabbit
Target Name: CXADR
Sample Tissue: Mouse Stomach lysates
Antibody Dilution: 1ug/ml
Rabbit Anti-CXADR Polyclonal Antibody – Cat# MBS3249886

Other Notes

Small volumes of anti-CXADR antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CXADR purchase

MBS3249886 is an antibody targeting CXADR. Also known as CXADR Antibody-middle region. Reactive in Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for CXADR. It may not necessarily be applicable to this product.

NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
UniProt Protein Name
Coxsackievirus and adenovirus receptor homolog
UniProt Gene Name
Cxadr
UniProt Synonym Gene Names
Car; CAR; mCAR

UniProt Comments for CXADR

Component of the epithelial apical junction complex that may function as a homophilic cell adhesion molecule and is essential for tight junction integrity. Also involved in transepithelial migration of leukocytes through adhesive interactions with JAML a transmembrane protein of the plasma membrane of leukocytes. The interaction between both receptors also mediates the activation of gamma-delta T-cells, a subpopulation of T-cells residing in epithelia and involved in tissue homeostasis and repair. Upon epithelial CXADR-binding, JAML induces downstream cell signaling events in gamma-delta T-cells through PI3-kinase and MAP kinases. It results in proliferation and production of cytokines and growth factors by T-cells that in turn stimulate epithelial tissues repair.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
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