Rabbit Anti-TMEM49 Polyclonal Antibody – Cat# MBS3249893

Host: Rabbit
Target Name: TMEM49
Sample Tissue: Mouse RAW264.7 Whole Cell lysates
Antibody Dilution: 1ug/ml

TMEM49 Antibody – Rabbit Polyclonal

Name: TMEM49 Antibody; Polyclonal; Rabbit; Mouse-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS3249893
Price: 490 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3249893

Description of Target: Stress-induced protein that, when overexpressed, promotes formation of intracellular vacuoles followed by cell death. May be involved in the cytoplasmic vacuolization of acinar cells during the early stage of acute pancreatitis.… More details

$490 / 0.1 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

TMEM49, Polyclonal Antibody

Full Product Name

TMEM49 Antibody-C-terminal region

Product Gene Name

anti-TMEM49 antibody

Product Synonym Names

vacuole membrane protein 1; ni-2; Tango5; Tmem49; mir-21a; AI787464; 3110098I04Rik; 4930579A11Rik

Immunogen Sequence

TPQGENWLSW MFEKLVVAMV CYFVLSIINS MAQNYAKRIQ QRLNSEEKTK

Clonality

Polyclonal

Host

Rabbit

Species Reactivity

Mouse

Form/Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Purity/Purification

Affinity Purified

Concentration

Batch dependent within range: 100ul at 0.5-1mg/ml (lot specific)

Preparation and Storage

For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Antibody/Peptide Pairs

TMEM49 peptide (MBS3249567) is used for blocking the activity of TMEM49 antibody (MBS3249893)

Molecular Weight

46kDa

3D Structure

ModBase 3D Structure for Q99KU0

Protein Size

406 amino acids

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of mouse TMEM49

Applications Tested/Suitable for anti-TMEM49 antibody

Western Blot (WB)

Other Notes

Small volumes of anti-TMEM49 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TMEM49 purchase

MBS3249893 is an antibody targeting TMEM49. Also known as TMEM49 Antibody-C-terminal region. Reactive in Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for TMEM49. It may not necessarily be applicable to this product.

NCBI GeneID

75909

NCBI Accession #

NM_029478.3

UniProt Primary Accession #

Q99KU0

UniProt Related Accession #

NP_083754.2

UniProt Protein Name

Vacuole membrane protein 1

UniProt Synonym Protein Names

NF-E2-inducible protein 2; Protein ni-2; Transmembrane protein 49

UniProt Gene Name

Vmp1

UniProt Synonym Gene Names

Tmem49; Protein ni-2

UniProt Entry Name

VMP1_MOUSE

UniProt Comments for TMEM49

VMP1: Stress-induced protein that, when overexpressed, promotes formation of intracellular vacuoles followed by cell death. May be involved in the cytoplasmic vacuolization of acinar cells during the early stage of acute pancreatitis. Plays a role in the initial stages of the autophagic process through its interaction with BECN1. Involved in cell-cell adhesion. Plays an essential role in formation of cell junctions. Interacts with BECN1. Interacts with TJP1. Interacts with TP53INP2. Belongs to the VMP1 family.

Protein type: Membrane protein, multi-pass; Membrane protein, integral; Endoplasmic reticulum

Cellular Component: endoplasmic reticulum; integral to membrane; membrane; nucleolus; plasma membrane; vacuole

Biological Process: autophagy; cell adhesion; cell-cell adhesion; embryo implantation; endoplasmic reticulum organization and biogenesis; exocytosis; Golgi organization and biogenesis; regulation of autophagy

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.