Acetylated Lysine Antibody – Rabbit Polyclonal

Acetylation of lysine is an important reversible modification. The activities of some proteins are controlled by acetylation of lysine. Histone acetyltransferases (HATs) acetylate the conserved amino-terminal domains of the four core histones (H2A, H2B, H3 and H4) that contain lysines residues. Histone deacetylases (HDACs) removes the acetyl group from the same residue. [1] Acetylation/deacetylation of histones results in cell signaling processes that include gene activity, cell growth, differentiation and apoptosis. [2] In cancer and polyglutamine diseases, the regulation of protein acetylation/deacetylation is impaired (7). Numerous anti-cancer drugs target HDACs. [3]

Small volumes of anti-Acetylated Lysine antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS330101 is an antibody targeting Acetylated Lysine. Also known as Anti-Acetylated Lysine, FITC. Host: Rabbit.