CD138 Antibody – Mouse Monoclonal

The DL-101 monoclonal antibody specifically reacts with human CD138, a 85-92 kDA type I heparan sulfate proteoglycan. CD138 is known as Syndecan-1 and is expressed on pre-B cells, immature B cells, plasma cells, and malignant plasma cells, to the exclusion of mature circulating B cells. Syndecan-1 is also expressed on vascular smooth muscle, endothelial, neural, and embryonic mesenchymal cells. It is involved in cellular proliferation, cellular migration, and acts as an extracellular matrix receptor. Among the hematopoietic elements, CD138 is a useful marker for plasma cells.

Gattei, V., Godeas, C., Degan, M., Rossi, F. M., Aldinucci, D., & Pinto, A. (1999). Characterization of anti?CD138 monoclonal antibodies as tools for investigating the molecular polymorphism of syndecan?1 in human lymphoma cells. British journal of haematology, 104(1), 152-162.
Fitzgerald, M. L., Wang, Z., Park, P. W., Murphy, G., & Bernfield, M. (2000). Shedding of syndecan-1 and-4 ectodomains is regulated by multiple signaling pathways and mediated by a TIMP-3-sensitive metalloproteinase. The Journal of cell biology, 148(4), 811-824.
Itoua Maïga, R., Lemieux, J., Roy, A., Simard, C., & Néron, S. (2014). Flow Cytometry Assessment of In Vitro Generated CD138< b>< sup>. BioMed research international, 2014.

Small volumes of anti-CD138 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS697051 is an antibody targeting CD138. Also known as Anti-Human CD138 (Syndecan-1) PE. Reactive in Human. Host: Mouse.