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CD94 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS335176

MBS335176 is an antibody targeting CD94. Also known as Mouse Anti-Human CD94 Monoclonal Antibody, Azide Free Clone B-D49. Reactive in Human. Host: Mouse. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
CD94, Monoclonal Antibody
Full Product Name
Mouse Anti-Human CD94 Monoclonal Antibody, Azide Free Clone B-D49
Product Gene Name
Product Synonym Names
CD94
Clonality
Monoclonal
Isotype
IgG1
Clone Number
B-D49
Host
Mouse
Species Reactivity
Human
Form/Format
Azide free
Phosphate-buffered saline. Sterile-filtered through 0.22 um. Carrier and preservative free
Purity/Purification
Ion exchange chromatography
Specificity
Recognizes cell surface CD94
Preparation and Storage
Stable at +2-8 degree C for 12 months. For longer storage, freeze aliquots.
Matching Pairs
Unconjugated Azide Free Antibody: CD94 Clone #B-D49 (MBS335176)
FITC Conjugated Antibody: CD94 Clone #B-D49 (MBS335183)
Matching Pairs
Unconjugated Azide Free Antibody: CD94 Clone #B-D49 (MBS335176)
Unconjugated Antibody: CD94 Clone #B-D49 (MBS335405)
Molecular Weight
17,109 Da
OMIM
602894
3D Structure
ModBase 3D Structure for Q13241
Antigen
CD94/ Kp43 / KLRD1
Hybridoma
Myeloma X63/AG.8653 x Balb/c spleen cells
Immunisation
IL-2 activated NK cells after tolerisation with activated PBL (CD56 negative)
Applications Tested/Suitable for anti-CD94 antibody
Flow Cytometry (FC/FACS), Immunohistochemistry (IHC)

Other Notes

Small volumes of anti-CD94 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CD94. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
CD94, partial
NCBI Official Synonym Full Names
killer cell lectin-like receptor subfamily D, member 1
NCBI Official Symbol
KLRD1
NCBI Official Synonym Symbols
CD94
UniProt Protein Name
Natural killer cells antigen CD94
UniProt Synonym Protein Names
KP43; Killer cell lectin-like receptor subfamily D member 1; NK cell receptor; CD_antigen: CD94
UniProt Gene Name
KLRD1
UniProt Synonym Gene Names
CD94
UniProt Entry Name
KLRD1_HUMAN
NCBI Protein Information
natural killer cells antigen CD94

NCBI Summary for CD94

Natural killer (NK) cells are a distinct lineage of lymphocytes that mediate cytotoxic activity and secrete cytokines upon immune stimulation. Several genes of the C-type lectin superfamily, including members of the NKG2 family, are expressed by NK cells and may be involved in the regulation of NK cell function. KLRD1 (CD94) is an antigen preferentially expressed on NK cells and is classified as a type II membrane protein because it has an external C terminus. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
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UniProt Comments for CD94

KLRD1: Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 12p13

Cellular Component: plasma membrane; integral to membrane; receptor complex; external side of plasma membrane

Molecular Function: protein binding; transmembrane receptor activity; carbohydrate binding

Biological Process: regulation of immune response; cell surface receptor linked signal transduction; natural killer cell mediated immunity; innate immune response
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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