IL-4 Antibody – Mouse Monoclonal

The 8D4-8 monoclonal antibody specifically reacts with human IL-4, expressed by the activated T cells and mast cells. IL-4 is species-specific and stimulates the proliferation and differentiation of B lymphocytes. It upregulates the expression of IgE receptors and class II MHC antigen. The 8D4-8 antibody neutralizes the IL-4 cytokine.

Bird, C., Wadhwa, M., & Thorpe, R. (1991). Development of immunoassays for human interleukin 3 and interleukin 4, some of which discriminate between different recombinant DNA-derived molecules. Cytokine, 3(6), 562-567.
Prussin, C., & Metcalfe, D. D. (1995). Detection of intracytoplasmic cytokine using flow cytometry and directly conjugated anti-cytokine antibodies. Journal of immunological methods, 188(1), 117-128.
Kon, O. M., Sihra, B. S., Till, S. J., Corrigan, C. J., Kay, A. B., & Grant, J. A. (1998). Unstimulated basophils in atopic and nonatopic subjects express intracellular interleukin?4: detection by flow cytometry. Allergy, 53(9), 891-896.

Small volumes of anti-IL-4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS697227 is an antibody targeting IL-4. Also known as Anti-Human IL-4 PE. Reactive in Human. Host: Mouse.