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CD109 Antibody – Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS335334

MBS335334 is an antibody targeting CD109. Also known as Mouse Anti-Human CD109 Monoclonal Antibody, Azide Free Clone B-E47. More details

$355 / 0.2 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CD109, Monoclonal Antibody
Full Product Name
Mouse Anti-Human CD109 Monoclonal Antibody, Azide Free Clone B-E47
Product Gene Name
Product Synonym Names
CD109
Clonality
Monoclonal
Isotype
Mouse IgG1 Kappa light chain
Clone Number
B-E47
Form/Format
Phosphate-buffered saline. Sterile-filtered through 0.22 um. Carrier and preservative free
Specificity
Recognises a 170 kDa protein
Preparation and Storage
Stable at +2-8°C for 12 months. For longer storage freeze aliquots.
Matching Pairs
Unconjugated Azide Free Antibody: CD109 Clone #B-E47 (MBS335334)
Unconjugated Antibody: CD109 Clone #B-E47 (MBS335337)
Matching Pairs
Unconjugated Azide Free Antibody: CD109 Clone #B-E47 (MBS335334)
PE Conjugated Antibody: CD109 Clone #B-E47 (MBS335428)
OMIM
608859
3D Structure
ModBase 3D Structure for Q6YHK3
Target Species
Human
Hybridoma
Myeloma X63/AG.8653 x Balb/c spleen cells
Immunisation
Eahy 926 cell line
Applications Tested/Suitable for anti-CD109 antibody
Flow Cytometry (FC)

Testing Data of anti-CD109 antibody

A typical staining pattern with the B-E47 monoclonal antibody of Eahy 926 cell line
Anti-CD109 Monoclonal Antibody – Cat# MBS335334

Other Notes

Small volumes of anti-CD109 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CD109. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
CD109 antigen isoform 3 preproprotein
NCBI Official Synonym Full Names
CD109 molecule
NCBI Official Symbol
CD109
NCBI Official Synonym Symbols
p180; r150; CPAMD7
UniProt Protein Name
CD109 antigen
UniProt Synonym Protein Names
150 kDa TGF-beta-1-binding protein; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 7; Platelet-specific Gov antigen; p180; r150; CD_antigen: CD109
Protein Family
UniProt Gene Name
CD109
UniProt Synonym Gene Names
CPAMD7
UniProt Entry Name
CD109_HUMAN
NCBI Protein Information
CD109 antigen

NCBI Summary for CD109

This gene encodes a glycosyl phosphatidylinositol (GPI)-linked glycoprotein that localizes to the surface of platelets, activated T-cells, and endothelial cells. The protein binds to and negatively regulates signalling by transforming growth factor beta (TGF-beta). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2014]
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UniProt Comments for CD109

CD109: Modulates negatively TGFB1 signaling in keratinocytes. Belongs to the protease inhibitor I39 (alpha-2- macroglobulin) family. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, GPI anchor

Chromosomal Location of Human Ortholog: 6q13

Cellular Component: extracellular space; cell surface; plasma membrane

Molecular Function: serine-type endopeptidase inhibitor activity; transforming growth factor beta binding

Biological Process: negative regulation of protein amino acid phosphorylation; hair follicle development; negative regulation of transforming growth factor beta receptor signaling pathway; regulation of keratinocyte differentiation
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-CD109 antibody

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