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Cyclin-Dependent Kinase 4 (CDK4) Antibody – Sheep Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS340090

Cyclin-dependent kinase 4 combines with the protein cyclin D to form a protein complex that promotes the passage of cells through the G1 checkpoint in the cell growth cycle. This cellular activity is regulated by the protein p16 produced by p16INK4a.… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
Cyclin-Dependent Kinase 4 (CDK4), Polyclonal Antibody
Full Product Name
Cyclin-Dependent Kinase 4 (CDK4)
Product Gene Name
Product Synonym Names
Cell division protein kinase 4; Cyclin-dependent kinase 4; PSK-J3; CDK4
Clonality
Polyclonal
Host
Sheep
Form/Format
Ig Fraction - Liquid
Concentration
>5mg/ml (U.V.abs @ 280nm) (lot specific)
Preparation and Storage
Upon delivery aliquot and store at -20 degree C. Avoid freeze / thaw cycles. Short term storage 2 - 8 degree C.
Molecular Weight
35,684 Da
3D Structure
ModBase 3D Structure for Q91727
Immunogen
Recombinant Human CDK4
Buffer
20mM Phosphate, 150mM Sodium Chloride
Preservative
0.09% Sodium Azide
ISO Certification
Manufactured in an ISO 13485:2016 Certified Laboratory.
Applications Tested/Suitable for anti-CDK4 antibody
ELISA (EIA), Western Blot (WB), Dot Blot (DB), Immunohistochemistry (IHC), Immunoassays, Development of Rapid tests and Other Immunoassay, Antibody Recognition Assays

Product References and Citations for anti-CDK4 antibody

Wolfel T. et al. (1995) Science 269: 1281-84.

Other Notes

Small volumes of anti-CDK4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CDK4 purchase

MBS340090 is an antibody targeting CDK4. Also known as Cyclin-Dependent Kinase 4 (CDK4). Host: Sheep.

Additional Details

NCBI/Uniprot data below describe general gene information for CDK4. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
cyclin-dependent kinase 4
NCBI Official Synonym Full Names
cyclin-dependent kinase 4 L homeolog
NCBI Official Symbol
cdk4.L
NCBI Official Synonym Symbols
cdk4; xcdk4
UniProt Protein Name
Cyclin-dependent kinase 4
UniProt Synonym Protein Names
Cell division protein kinase 4
UniProt Gene Name
cdk4
UniProt Entry Name
CDK4_XENLA
NCBI Protein Information
cyclin-dependent kinase 4

UniProt Comments for CDK4

Function: Probably involved in the control of the cell cycle.

Catalytic activity: ATP + a protein = ADP + a phosphoprotein.

Enzyme regulation: Phosphorylation at Thr-172 is necessary for enzymatic activity

Subunit structure: Forms a stable complex with D-type G1 cyclins

Sequence similarities: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.Contains 1 protein kinase domain.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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