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Fractalkine (CX3CL1) Antibody – Sheep Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS340794

MBS340794 is an antibody targeting CX3CL1. Also known as Fractalkine Affinity Purified. Host: Sheep. Polyclonal Fractalkine Antibody More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
Fractalkine (CX3CL1), Polyclonal Antibody
Full Product Name
Fractalkine Affinity Purified
Product Gene Name
anti-CX3CL1 antibody
Product Synonym Names
Fractalkine; cx3cl1; C-X3-C motif chemokine 1; Neurotactin; CX3C membrane-anchored chemokine; Small-inducible cytokine D2
Clonality
Polyclonal
Host
Sheep
Form/Format
Affinity Purified Ig
Concentration
>5mg/ml (U.V.abs @ 280nm) (lot specific)
Preparation and Storage
Upon delivery aliquot and store at -20 degree C. Avoid freeze / thaw cycles. Short term storage 2 - 8 degree C.
Molecular Weight
42,203 Da
OMIM
601880
Immunogen
Recombinant Human Fractalkine
Buffer
20mM Phosphate, 150mM Sodium Chloride
Preservative
0.09% Sodium Azide

Product Categories/Family for anti-CX3CL1 antibody

Polyclonal Antibodies; Biochemical Markers; Proteins; Fractalkine
ISO Certification
Manufactured in an ISO 13485:2016 Certified Laboratory.
Applications Tested/Suitable for anti-CX3CL1 antibody
ELISA (EIA), Western Blot (WB), Dot Blot (DB), Immunohistochemistry (IHC), Immunoassays, Development of Rapid tests and Other Immunoassay, Antibody Recognition Assays

Other Notes

Small volumes of anti-CX3CL1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CX3CL1. It may not necessarily be applicable to this product.

NCBI GI #
4506857
NCBI GeneID
6376
NCBI Accession #
NP_002987.1
UniProt Secondary Accession #
O00672
UniProt Related Accession #
P78423
GenBank Nucleotide #
NM_002996.4
NCBI Official Full Name
fractalkine isoform 1
NCBI Official Synonym Full Names
C-X3-C motif chemokine ligand 1
NCBI Official Symbol
CX3CL1
NCBI Official Synonym Symbols
NTN; NTT; CXC3; CXC3C; SCYD1; ABCD-3; C3Xkine; fractalkine; neurotactin
UniProt Protein Name
Fractalkine
UniProt Synonym Protein Names
C-X3-C motif chemokine 1; CX3C membrane-anchored chemokine; Neurotactin; Small-inducible cytokine D1
Protein Family
Fractalkine
UniProt Gene Name
CX3CL1
UniProt Synonym Gene Names
FKN; NTT; SCYD1
UniProt Entry Name
X3CL1_HUMAN
NCBI Protein Information
fractalkine

UniProt Comments for CX3CL1

CX3CL1: The soluble form is chemotactic for T-cells and monocytes, but not for neutrophils. The membrane-bound form promotes adhesion of those leukocytes to endothelial cells. May play a role in regulating leukocyte adhesion and migration processes at the endothelium. Binds to CX3CR1. Belongs to the intercrine delta family.

Protein type: Membrane protein, integral; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 16q13

Cellular Component: cell surface; extracellular region; extracellular space; integral to membrane; plasma membrane

Molecular Function: CCR chemokine receptor binding; chemokine activity; CX3C chemokine receptor binding; integrin binding; protein binding; receptor binding

Biological Process: chemotaxis; cytokine and chemokine mediated signaling pathway; defense response; G-protein coupled receptor protein signaling pathway; immune response; integrin activation; leukocyte adhesive activation; leukocyte chemotaxis; leukocyte migration during inflammatory response; lymphocyte chemotaxis; monocyte chemotaxis; neutrophil chemotaxis; positive regulation of calcium-independent cell-cell adhesion; positive regulation of GTPase activity; positive regulation of inflammatory response
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Research Articles on CX3CL1

1. CX3CL1(+) apo-MPs released by apoptotic cells mediate the chemotactic transmigration of alveolar macrophages.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-CX3CL1 antibody

 Reference Product  PubMed Publications
 CX3CR1 antibody  >578 publications with CX3CL1 and CX3CR1
 CCR2 antibody  >72 publications with CX3CL1 and CCR2
 CCR5 antibody  >41 publications with CX3CL1 and CCR5
 CXCR3 antibody  >33 publications with CX3CL1 and CXCR3
 CCR1 antibody  >22 publications with CX3CL1 and CCR1
 CXCR2 antibody  >14 publications with CX3CL1 and CXCR2
 CCR7 antibody  >13 publications with CX3CL1 and CCR7
 CCR3 antibody  >13 publications with CX3CL1 and CCR3
 CXCR1 antibody  >11 publications with CX3CL1 and CXCR1

Pathways associated with anti-CX3CL1 antibody

 Products by Pathway  Pathway Diagram
 Chemokine Receptors Bind Chemokines Pathway antibodies  Chemokine Receptors Bind Chemokines Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Direct P53 Effectors Pathway antibodies  Direct P53 Effectors Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 Peptide Ligand-binding Receptors Pathway antibodies  Peptide Ligand-binding Receptors Pathway Diagram
 Signal Transduction Pathway antibodies  Signal Transduction Pathway Diagram

Diseases associated with anti-CX3CL1 antibody

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >397 publications with CX3CL1 and Inflammation
 Necrosis Antibodies  >202 publications with CX3CL1 and Necrosis
 Cardiovascular Diseases Antibodies  >179 publications with CX3CL1 and Cardiovascular Diseases
 Disease Models, Animal Antibodies  >161 publications with CX3CL1 and Disease Models, Animal
 Atherosclerosis Antibodies  >104 publications with CX3CL1 and Atherosclerosis
 Lung Diseases Antibodies  >78 publications with CX3CL1 and Lung Diseases
 Pain Antibodies  >71 publications with CX3CL1 and Pain
 Heart Diseases Antibodies  >65 publications with CX3CL1 and Heart Diseases
 Kidney Diseases Antibodies  >65 publications with CX3CL1 and Kidney Diseases
 Liver Diseases Antibodies  >57 publications with CX3CL1 and Liver Diseases

Organs/Tissues associated with anti-CX3CL1 antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >221 publications with CX3CL1 and Brain
 Muscle Antibodies  >102 publications with CX3CL1 and Muscle
 Kidney Antibodies  >95 publications with CX3CL1 and Kidney
 Lung Antibodies  >94 publications with CX3CL1 and Lung
 Heart Antibodies  >78 publications with CX3CL1 and Heart
 Liver Antibodies  >75 publications with CX3CL1 and Liver
 Nerve Antibodies  >56 publications with CX3CL1 and Nerve
 Skin Antibodies  >46 publications with CX3CL1 and Skin
 Intestine Antibodies  >36 publications with CX3CL1 and Intestine
 Eye Antibodies  >32 publications with CX3CL1 and Eye
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