Soluble Tumor Necrosis Factor Receptor 2 (STNF-R2) Recombinant Protein

Two types of soluble TNF receptors (sTNFR-I and sTNFR-II) have been identified, which act to neutralize the biological activities of TNFalpha and TNF beta. Levels of these soluble receptors appear to arise as a result of shedding of the extracellular domains of the membrane bound receptors. Elevated levels of soluble TNF receptors have been found in the amniotic fluid of pregnant women. Recombinant sTNFR-I comprises a 161 amino acid fragment (41-201) corresponding to the mature sTNFR-I protein and is expressed in E Coli with an amino-terminal hexahistidine tag. This product is not intended for therapeutic use.

Wallach, D. et al., (1991) Agents Actions Suppl. 35: 51- 57

Small volumes of STNF-R2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS343136 is a recombinant protein targeting STNF-R2. Also known as Soluble Tumor Necrosis Factor Receptor 2 (STNF-R2).