Pres1 (HBV) Antibody – Mouse Monoclonal

Background: Hepatitis B virus (HBV), is a species of the genus Orthohepadnavirus, which is likewise a part of the Hepadnaviridae family of viruses. This virus causes the disease hepatitis B which is an infectious inflammatory illness of the liver and affects hominoidea, including humans. There are four known genes encoded by the genome called C, X, P, and S. Gene S is the gene that codes for the surface antigen (HBsAg). And HBsAg gene is one long open reading frame but contains three in frame "start" (ATG) codons that divide the gene into three sections, pre-S1, pre-S2, and S. The double interaction between the HBV capside and both S and pre-S1 domains may be required for virion morphogenesis.

1. Hunt, Richard (2007-11-21). "Hepatitis viruses". University of Southern California, Department of Pathology and Microbiology. Retrieved 2008-03-13. 2. Hassan MM, Li D, El-Deeb AS, et al. (October 2008). "Association between hepatitis B virus and pancreatic cancer". J. Clin. Oncol. 26 (28): 4557-62. 3. Francis poisson, Anne severac, Christophe hourioux, Alain goudeau, Philippe roingeard. Both Pre-S1 and S Domains of Hepatitis B Virus Envelope Proteins Interact with the Core Particle. Virology. Volume 228, Issue 1, 3 February 1997, Pages 115-120.

Small volumes of anti-HBV-preS1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS355001 is an antibody targeting HBV-preS1. Also known as HBV-PreS1 (Capture Ab). Reactive in Human. Host: Mouse.