Rabbit Anti-DCHS1 Polyclonal Antibody – Cat# MBS355055

Protocadherin-16 (DCHS1) Antibody – Rabbit Polyclonal

Name: DCHS1 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS355055
Price: 370 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS355055

Protocadherin-16 (PCDH16), as known as Protein dachsous homolog 1 or cadherin-19 (CDH19) or cadherin-25 (CDH25) or fibroblast cadherin-1 (FIB1), is a protein that in humans is encoded by the DCHS1 gene.[1] This gene is a member of the cadherin superfamily… More details

DISCONTINUED
Click here to view our similar product(s) OR click here to contact our technical support team for suitable replacement.

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

Protocadherin-16 (DCHS1), Polyclonal Antibody

Full Product Name

Anti-Protocadherin-16 antibody

Product Gene Name

anti-DCHS1 antibody

Product Synonym Names

Polyclonal Anti- Protocadherin-16

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Liquid

Purity/Purification

Immunogen affinity purified

Preparation and Storage

Store at 4 degree C after thawing (1 week). Aliquot and store at -20 degree C for long term (at least one year). Avoid repeated freeze and thaw cycles.

Molecular Weight

346,181 Da

Chromosome Location

Chromosome: 11; NC_000011.9 (6642556..6685320, complement). Location: 11p15.4

OMIM

603057

3D Structure

ModBase 3D Structure for Q96JQ0

Immunogen

A synthetic peptide (conjugated with KLH) corresponding to the region of human Protocadherin-16.

Storage Buffer

In TBS (pH7.4), 0.5% BSA, 40% Glycerol and 0.05% Sodium Azide.

Applications Tested/Suitable for anti-DCHS1 antibody

Western Blot (WB), Immunocytochemistry (ICC)

Application Notes for anti-DCHS1 antibody

WB (1:500-1000); ICC (1:50-100)

Product References and Citations for anti-DCHS1 antibody

1. Matsuyoshi N, Imamura S (June 1997). "Multiple cadherins are expressed in human fibroblasts". Biochem. Biophys. Res. Commun. 235 (2): 355-8. 2. Burbano, H. A., Hodges, E., Green, R. E., Briggs, A. W., Krause, J., Meyer, M., Good, J. M., Maricic, T., Johnson, P. L. F., Xuan, Z., Rooks, M., Bhattacharjee, A., Brizuela, L., Albert, F. W., de la Rasilla, M., Fortea, J., Rosas, A., Lachmann, M., Hannon, G. J., Paabo, S. Targeted investigation of the Neandertal genome by array-based sequence capture. Science 328: 723-725, 2010.

Other Notes

Small volumes of anti-DCHS1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for DCHS1 purchase

MBS355055 is an antibody targeting DCHS1. Also known as Anti-Protocadherin-16 antibody. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for DCHS1. It may not necessarily be applicable to this product.

NCBI GI #

16933557

NCBI GeneID

8642

NCBI Accession #

NP_003728.1

UniProt Primary Accession #

Q96JQ0

UniProt Secondary Accession #

O15098

UniProt Related Accession #

Q96JQ0

GenBank Nucleotide #

NM_003737.2

NCBI Official Full Name

protocadherin-16

NCBI Official Synonym Full Names

dachsous 1 (Drosophila)

NCBI Official Symbol

DCHS1

NCBI Official Synonym Symbols

FIB1; CDH25; CDHR6; PCDH16

UniProt Protein Name

Protocadherin-16

UniProt Synonym Protein Names

Cadherin-19; Cadherin-25; Fibroblast cadherin-1; Protein dachsous homolog 1

Protein Family

Protocadherin

UniProt Gene Name

DCHS1

UniProt Synonym Gene Names

CDH19; CDH25; FIB1; KIAA1773; PCDH16

UniProt Entry Name

PCD16_HUMAN

NCBI Protein Information

protocadherin-16; cadherin-19; cadherin-25; protocadherin 16; fibroblast cadherin 1; fibroblast cadherin-1; fibroblast cadherin FIB1; protein dachsous homolog 1; cadherin-related family member 6

NCBI Summary for DCHS1

This gene is a member of the cadherin superfamily whose members encode calcium-dependent cell-cell adhesion molecules. The encoded protein has a signal peptide, 27 cadherin repeat domains and a unique cytoplasmic region. This particular cadherin family member is expressed in fibroblasts but not in melanocytes or keratinocytes. The cell-cell adhesion of fibroblasts is thought to be necessary for wound healing. [provided by RefSeq, Jul 2008]

UniProt Comments for DCHS1

Function: Calcium-dependent cell-adhesion protein

Potential.

Subcellular location: Cell membrane; Single-pass type I membrane protein

By similarity.

Tissue specificity: Fibroblast specific.

Sequence similarities: Contains 27 cadherin domains.

Sequence caution: The sequence BAB61903.2 differs from that shown. Reason: Erroneous initiation.

Research Articles on DCHS1

1. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with anti-DCHS1 antibody

Disease Name	Pubmed Publications
Kidney Diseases Antibodies	>1 publications with DCHS1 and Kidney Diseases

Organs/Tissues associated with anti-DCHS1 antibody

Organ/Tissue Name	Pubmed Publications
Kidney Antibodies	>3 publications with DCHS1 and Kidney
Brain Antibodies	>3 publications with DCHS1 and Brain
Nerve Antibodies	>2 publications with DCHS1 and Nerve
Intestine Antibodies	>2 publications with DCHS1 and Intestine
Lung Antibodies	>2 publications with DCHS1 and Lung
Heart Antibodies	>1 publications with DCHS1 and Heart
Eye Antibodies	>1 publications with DCHS1 and Eye
Embryonic Tissue Antibodies	>1 publications with DCHS1 and Embryonic Tissue