Calcineurin (CAN) ELISA Kit for Mouse

Name: Mouse CAN ELISA Kit; Calcineurin; MyBioSource
Brand: MyBioSource
SKU: MBS035523
Price: 675 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS035523

MBS035523 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Calcineurin (CAN) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive… More details

$675 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Request Current Manual

Product Overview

Online Datasheet in PDF

Product Name

Calcineurin (CAN), ELISA Kit

Full Product Name

Mouse Calcineurin ELISA Kit

Product Gene Name

CAN elisa kit

Species Reactivity

Mouse

Assay Type

Sandwich

Preparation and Storage

Store all reagents at 2-8 degree C

Molecular Weight

69,133 Da

3D Structure

ModBase 3D Structure for P48456

Other Notes

Small volumes of CAN elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CAN. It may not necessarily be applicable to this product.

NCBI GI #

442622005

NCBI GeneID

43670

NCBI Accession #

NP_001247378.2

UniProt Primary Accession #

P48456

UniProt Secondary Accession #

Q8MQN3; Q9TY69; Q9VA20

UniProt Related Accession #

P48456

GenBank Nucleotide #

NM_001260449.2

NCBI Official Full Name

calcineurin A1, isoform D

NCBI Official Synonym Full Names

Calcineurin A1

NCBI Official Symbol

CanA1

NCBI Official Synonym Symbols

Can; CAN A1/PP2B; canA; Cana1; CG1455; CnA; CNA1; CnnA21EF; D14; DmCanA1-100B; DmelCG1455; pMY4; PP2B; PP2B 21EF; PpD14

UniProt Protein Name

Serine/threonine-protein phosphatase 2B catalytic subunit 1

UniProt Synonym Protein Names

Calmodulin-dependent calcineurin A1 subunit

Protein Family

Calcineurin

UniProt Gene Name

CanA1

UniProt Synonym Gene Names

CNA1; PpD14

UniProt Entry Name

PP2B1_DROME

NCBI Protein Information

CG1455 gene product from transcript CG1455-RD; CG1455-PA; CG1455-PB; CG1455-PD; CanA1-PA; CanA1-PB; CanA1-PD; calcineurin; calcineurin A; calcineurin A1; protein phosphatase D14; protein phosphatase from PCR fragment D14

UniProt Comments for CAN

Function: Calcium-dependent, calmodulin-stimulated protein phosphatase. This subunit may have a role in the calmodulin activation of calcineurin.

Catalytic activity: [a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactor: Binds 1 Fe3+ ion per subunit

By similarity.Binds 1 zinc ion per subunit

By similarity.

Subunit structure: Composed of two components (A and B), the A component is the catalytic subunit and the B component confers calcium sensitivity.

Sequence similarities: Belongs to the PPP phosphatase family. PP-2B subfamily.

Sequence caution: The sequence AAA28410.1 differs from that shown. Reason: Erroneous initiation.

Research Articles on CAN

1. upregulation of Nebula/DSCR1 is neuroprotective in the presence of APP upregulation and provides evidence for calcineurin inhibition as a novel target for therapeutic intervention in preventing axonal transport impairments associated with AD.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with CAN elisa kit

Products by Pathway	Pathway Diagram
Ca2+ Pathway antibodies	Ca2+ Pathway Diagram
DARPP-32 Events Pathway antibodies	DARPP-32 Events Pathway Diagram
FCERI Mediated Ca+2 Mobilization Pathway antibodies	FCERI Mediated Ca+2 Mobilization Pathway Diagram
Fc Epsilon Receptor (FCERI) Signaling Pathway antibodies	Fc Epsilon Receptor (FCERI) Signaling Pathway Diagram
Immune System Pathway antibodies	Immune System Pathway Diagram
Innate Immune System Pathway antibodies	Innate Immune System Pathway Diagram
Opioid Signalling Pathway antibodies	Opioid Signalling Pathway Diagram
Signal Transduction Pathway antibodies	Signal Transduction Pathway Diagram
Signaling By GPCR Pathway antibodies	Signaling By GPCR Pathway Diagram
Signaling By Wnt Pathway antibodies	Signaling By Wnt Pathway Diagram