FGF acidic Recombinant Protein

Recombinant human FGF acidic / FGF1 protein with molecular weight 15.3kDa.
Fibroblast growth factor, acidic (FGFA) also know as Fibroblast growth factor 1 (FGF1) is expressed in the proliferative and hypertrophic zones of human cartilage. It is the prototype of the 22-member FGF family of proteins and has been implicated in a range of physiological processes, including development, wound healing and cardiovascular changes. The intracellular mammalian FGF1 was phosphorylated on a single phosphorylation site (ser130), and that phosphorylation occurred in the nucleus following activation and nuclear import of protein kinase C-delta (PRKCD). Phosphorylated FGF1 was then exported to the cytosol via exportin-1 (XPO1).

1. Theil, E. (1987). "Ferritin: structure, gene regulation, and cellular function in animals, plants, and microorganisms.". Annual review of biochemistry 56 (1): 289-315. 2. Pham, C. G., Bubici, C., Zazzeroni, F., Papa, S., Jones, J., Alvarez, K., Jayawardena, S., De Smaele, E., Cong, R., Beaumont, C., Torti, F. M., Torti, S. V., Franzoso, G. Ferritin heavy chain upregulation by NF-kappa-B inhibits TNF-alpha-induced apoptosis by suppressing reactive oxygen species. Cell 119: 529-542, 2004.

Small volumes of FGF acidic recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS355572 is a recombinant protein targeting FGF acidic. Also known as FGF acidic, FGF1 Protein (Active). Host: E Coli.