FGF basic Active Protein

Recombinant human basic FGF / FGF2 protein with molecular weight 18 kDa.
Fibroblast growth factor, basic (FGFB) also know as Fibroblast growth factor 2 (FGF2) is a wide-spectrum mitogenic, angiogenic, and neurotrophic factor that is expressed at low levels in many tissues and cell types and reaches high concentrations in brain and pituitary. FGF-2 participates in controlling fates, migration and differentiation of neuronal cells, whereas it is not essential for their proliferation. FGF-2 accelerates fracture healing and prevents nonunion in primates, and therefore propose that it is a potent bone anabolic agent for clinical use. It could also be used in vivo to facilitate the mobilization and differentiation of resident cardiac precursors in the treatment of cardiac diseases

1. Dono, R., Texido, G., Dussel, R., Ehmke, H., Zeller, R. Impaired cerebral cortex development and blood pressure regulation in FGF2-deficient mice. EMBO J. 17: 4213-4225, 1998. 2. Kawaguchi, H., Nakamura, K., Tabata, Y., Ikada, Y., Aoyama, I., Anzai, J., Nakamura, T., Hiyama, Y., Tamura, M. Acceleration of fracture healing in nonhuman primates by fibroblast growth factor-2. J. Clin. Endocr. Metab. 86: 875-880, 2001. 3. Rosenblatt-Velin, N., Lepore, M. G., Cartoni, C., Beermann, F., Pedrazzini, T. FGF-2 controls the differentiation of resident cardiac precursors into functional cardiomyocytes. J. Clin. Invest. 115: 1724-1733, 2005.

Small volumes of FGF basic active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS355638 is an active protein targeting FGF basic. Also known as FGF basic, FGF2 Protein (Active). Host: E Coli.