Chlortetracycline Antibody – Mouse Monoclonal

Chlortetracycline is a tetracycline antibiotic, the first tetracycline to be identified. It was discovered in 1945 by Benjamin Minge Duggar working at Lederle Laboratories under the supervision of Yellapragada Subbarow. Serum chlortetracycline (CTC) concentration in dromedary camels increases within 1 hour after intrauterine administration and remains elevated for at least 72 hours in control, oxytocin-, and PGF2alpha-treated animals. Pulicharla R et al investigated the stability constants and toxicity of chlortetracycline (CTC) and metal (Ca, Mg, Cu and Cr) complexes. Their study provides evidence that CTC and its metal complexes are toxic to bacteria when they are biologically available. As for WWS, CTC was adsorbed to solid part and was not biologically available to show measurable toxic effects.

1. Jukes, Thomas H. Some historical notes on chlortetracycline. Reviews of Infectious Diseases 7(5):702-707 (1985).
2. Ghoneim IM, Abdelghany AM, Waheed MM, Elmoslemany AM, Alhaider AK, Al-Eknah MM. Effect of oxytocin and PGF2alpha on chlortetracycline absorption from the uterus of early postpartum camels (Camelus dromedarius). Theriogenology. 2015 Sep 1;84(4):645-9.
3. Pulicharla R, Das RK, Brar SK, Drogui P, Sarma SJ, Verma M, Surampalli RY, Valero JR. Toxicity of chlortetracycline and its metal complexes to model microorganisms in wastewater sludge. Sci Total Environ. 2015 Nov 1;532:669-75.

Small volumes of anti-Chlortetracycline antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS355768 is an antibody targeting Chlortetracycline. Also known as Monoclonal Anti-Chlortetracycline. Host: Mouse.