Ochratoxin A Antibody – Mouse Monoclonal

Ochratoxins are a group of mycotoxins produced by some Aspergillus species and some Penicillium species, especially P. verrucosum and P. carbonarius. Ochratoxin A is the most prevalent and relevant fungal toxin of this group, while ochratoxins B and C are of lesser importance. Ochratoxin A (OTA), a toxin produced by several species of Aspergillus and Penicillium, is one of the most abundant food-contaminating mycotoxins. There were high levels of OTA contaminations in wheat in the areas with high incidence of esophageal cancer in north China. This finding suggests that exposure to low levels of OTA may be a critical etiological factor for esophageal cancer in these areas. It could induce DNA damage, G2 arrest and apoptosis in Het-1A cells, which may be involved in the esophageal toxicity of OTA. OTA in red chili peppers may be associated with the development of gallbladder cancer.

1. Liu J, Wu S, Shen H, Cui J, Wang Y, Xing L, Wang J, Yan X, Zhang X. Ochratoxin A induces DNA damage and G2 phase arrest in human esophageal epithelium Het-1A cells in vitro. J Toxicol Sci. 2015;40(5):657-65.
2. Ikoma T, Tsuchiya Y, Asai T, Okano K, Ito N, Endoh K, Yamamoto M, Nakamura K. Ochratoxin A Contamination of Red Chili Peppers from Chile, Bolivia and Peru, Countries with a High Incidence of Gallbladder Cancer. Asian Pac J Cancer Prev. 2015;16(14):5987-91.

Small volumes of anti-Ochratoxin A antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS355774 is an antibody targeting Ochratoxin A. Also known as Ochratoxin A (Mouse monoclonal). Host: Mouse.